Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794887 | 0.80 | RAB9A (0.60) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL5788078 | 0.80 | RAB9A (0.43) | MAPTIDO1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23794894 | 0.80 | AURKA (0.49) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL23794891 | 0.80 | MAPK10 (0.50) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL5765529 | 0.79 | KMT2A (0.50) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL23794897 | 0.76 | ROCK1 (0.51) | MAPTIDO1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23794892 | 0.76 | KMT2A (0.48) | KMT2AKCNH2SCN9ASCN5A | |
| SCHEMBL23794896 | 0.76 | RAB9A (0.59) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL20600105 | 0.72 | KDM1A (0.61) | MAPTMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL5801454 | 0.70 | CA1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |