Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794891 | 0.79 | MAPK10 (0.50) | KMT2AKCNH2SCN5ASCN9A | |
| SCHEMBL5788078 | 0.76 | RAB9A (0.43) | KMT2A | |
| SCHEMBL23794893 | 0.76 | MAPT (0.48) | KMT2AKCNH2SCN5ASCN9A | |
| SCHEMBL23794887 | 0.76 | RAB9A (0.60) | KMT2A | |
| SCHEMBL23794894 | 0.76 | AURKA (0.49) | KMT2A | |
| SCHEMBL5765529 | 0.75 | KMT2A (0.50) | KMT2A | |
| SCHEMBL1921455 | 0.73 | EPHX2 (0.56) | KMT2ADHODHEPHX2 | |
| SCHEMBL394422 | 0.73 | EPHX2 (0.56) | KMT2ADHODHEPHX2 | |
| SCHEMBL23794897 | 0.71 | ROCK1 (0.51) | KMT2A | |
| SCHEMBL23794896 | 0.71 | RAB9A (0.59) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3876933-A1 | NEUTROPHIL INFLAMMATION INHIBITOR AND USES THEREOF | Chang Gung University of Science and Technology (TW) | 2021-09-15 | — | — | EP | disclosed |