Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.49 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.49 |
| ▸ | F10 known ✓ | P00742 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | F12 | P00748 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705963 | 1.00 | KMT2A (0.56) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL2379364 | 1.00 | KMT2A (0.56) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL9764075 | 0.98 | KMT2A (0.53) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| Potassium Ion SCHEMBL9183921 | 0.97 | KMT2A (0.56) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL5696715 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL38661498 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL5696798 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL5696854 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL15549028 | 0.87 | KMT2A (0.68) | KMT2ASMN1; SMN2NPC1RAB9AESR1 | |
| SCHEMBL18162002 | 0.86 | KMT2A (0.59) | KMT2ASMN1; SMN2NPC1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386340-B | Detergent compositions comprising polypeptide variants | 宝洁公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117683748-A | Detergent compositions comprising polypeptide variants | 宝洁公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-111386340-A | Detergent compositions comprising polypeptide variants | 宝洁公司 | 2020-07-07 | — | — | CN | disclosed |
| CN-111247245-A | Detergent compositions comprising polypeptide variants | 宝洁公司 | 2020-06-05 | — | — | CN | disclosed |
| US-9435073-B2 | Electrochemical textile-washing process | BASF SE (DE) | 2016-09-06 | — | — | US | disclosed |
| US-20140346057-A1 | ELECTROCHEMICAL TEXTILE-WASHING PROCESS | BASF SE (DE) | 2014-11-27 | — | — | US | disclosed |
| WO-2013034548-A1 | METHOD FOR BLEACHING KITCHEN UTENSILS IN A DISHWASHER | BASF SE (DE) | 2013-03-14 | — | — | WO | disclosed |
| US-20130056364-A1 | METHOD FOR THE BLEACHING OF KITCHENWARE IN A DISHWASHER | BASF SE (DE) | 2013-03-07 | — | — | US | disclosed |
| US-20110237484-A1 | ELECTROCHEMICAL TEXTILE-WASHING PROCESS | BASF SE (DE) | 2011-09-29 | — | — | US | disclosed |