Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.33 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL23853413 | 0.96 | HTT (0.39) | BDKRB2HTTDNM1L3MBTL1TLR8 | |
| Hydrochloric Acid SCHEMBL23852343 | 0.96 | BDKRB2 (0.40) | BDKRB2HTTDNM1L3MBTL1TLR8 | |
| Hydrochloric Acid SCHEMBL6310910 | 0.94 | HTT (0.42) | BDKRB2HTTDNM1L3MBTL1TLR8 | |
| Bromide SCHEMBL7196672 | 0.94 | HRH3 (0.39) | BDKRB2HTTDNM1L3MBTL1TLR8 | |
| Bromide SCHEMBL7611775 | 0.91 | HIF1A (0.47) | HTTDNM1HIF1ATRAP1 | |
| Bromide SCHEMBL131195 | 0.81 | HIF1A (0.58) | BDKRB2DNM1HIF1ATRAP1 | |
| Bromide SCHEMBL23038696 | 0.81 | TRAP1 (0.34) | TRAP1 | |
| Bromide SCHEMBL1866839 | 0.79 | HIF1A (0.56) | DNM1HIF1ATRAP1 | |
| Bromide SCHEMBL7759526 | 0.79 | HIF1A (0.56) | DNM1HIF1ATRAP1 | |
| Bromide SCHEMBL164301 | 0.79 | HIF1A (0.56) | DNM1HIF1ATRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885334-B1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | SHINETSU CHEMICAL CO (JP) | 2023-01-11 | — | — | EP | disclosed |
| US-11420919-B2 | Process for preparing a formylalkenyl alkoxymethyl ether compound and processes for preparing conjugated diene compounds from the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-08-23 | — | — | US | disclosed |
| US-20210300854-A1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2021-09-30 | — | — | US | disclosed |
| EP-3885334-A1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2021-09-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210300854-A1 | PROCESS FOR PREPARING A FORMYLALKENYL ALKOXYMETHYL ETHER COMPOUND AND PROCESSES FOR PREPARING CONJUGATED DIENE COMPOUNDS FROM THE SAME | ADH1C, ORC3, ADH1A | ACHE 1699/4885BDKRB2 1197/4885HTT 4482/4885 |
| US-11420919-B2 | Process for preparing a formylalkenyl alkoxymethyl ether compound and processes for preparing conjugated diene compounds from the same | ADH1C, ORC3, ADH1A | ACHE 1699/4885BDKRB2 1197/4885HTT 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.