Sugi Predict

Sugi Predict / Compounds / SCHEMBL2386657

SCHEMBL2386657

SCHEMBL2386657

CC(C)(C)OC(=O)N(OCC(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HDAC6 Q9UBN7 2/20 0.43
▸ HDAC1 Q13547 1/20 0.43
▸ HDAC2 Q92769 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ NFKB2 Q00653 1/20 0.33
▸ RELA Q04206 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.32
▸ TSHR P16473 1/20 0.31
▸ CTH P32929 1/20 0.31
▸ CBS P35520 1/20 0.31
▸ THPO P40225 1/20 0.31
▸ DGAT1 O75907 1/20 0.30
▸ THRB P10828 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ HMGCR P04035 1/20 0.30
▸ CHRM1 P11229 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31476759 0.82 HDAC6 (0.35) HDAC6HDAC1HDAC2L3MBTL1CA14
SCHEMBL7177266 0.79 HDAC6 (0.35) HDAC6HDAC1HDAC2L3MBTL1CA14
SCHEMBL12028867 0.73 HDAC6 (0.42) HDAC6HDAC1HDAC2L3MBTL1NFKB1
SCHEMBL13225176 0.73 HDAC6 (0.36) HDAC6HDAC1HDAC2CA14GAA
SCHEMBL4178314 0.72 HDAC6 (0.47) HDAC6HDAC1HDAC2NFKB1NFKB2
SCHEMBL31454668 0.71 NFKB1 (0.32) NFKB1NFKB2RELA
SCHEMBL4403092 0.71 L3MBTL1 (0.58) HDAC1HDAC2L3MBTL1CA14SMN1; SMN2
SCHEMBL12029092 0.71 HDAC6 (0.44) HDAC6HDAC1HDAC2L3MBTL1NFKB1
SCHEMBL10439172 0.71 HDAC6 (0.40) HDAC6HDAC1HDAC2NFKB1NFKB2
SCHEMBL19153581 0.70 HDAC6 (0.46) HDAC6HDAC1HDAC2NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375015-B Preparation method of di-tert-butyloxycarbonyl aminooxy acetic acid 安徽昊帆生物有限公司 2023-09-19 — — CN claimed
CN-112375015-A Preparation method of di-tert-butyloxycarbonylaminoacetic acid 安徽昊帆生物有限公司 2021-02-19 — — CN claimed
US-20030027722-A1 Influencing the activity of plant growth regulators PLANT RESEARCH INTERNATIONAL B.V. (NL) 2003-02-06 — — US claimed
US-20250041439-A1 ANTIBODY-DRUG CONJUGATES SPIREA LIMITED (GB) 2025-02-06 — — US disclosed
US-20230355737-A1 PARTICLE COMPRISING AN RSV-F PROTEIN FOR USE IN RSV VACCINATION VIROMETIX AG (CH) 2023-11-09 — — US disclosed
CN-112375015-B Preparation method of di-tert-butyloxycarbonyl aminooxy acetic acid 安徽昊帆生物有限公司 2023-09-19 — — CN disclosed
EP-4216992-A1 PARTICLE COMPRISING AN RSV-F PROTEIN FOR USE IN RSV VACCINATION DBV Technologies (FR) 2023-08-02 — — EP disclosed
US-20230173092-A1 ANTIBODY-DRUG CONJUGATES SPIREA LIMITED (GB) 2023-06-08 — — US disclosed
WO-2022063990-A1 PARTICLE COMPRISING AN RSV-F PROTEIN FOR USE IN RSV VACCINATION DBV TECHNOLOGIES (FR) 2022-03-31 — — WO disclosed
CN-113260377-A Lipopeptide building blocks and synthetic virus-like particles 维罗米蒂克斯股份公司 2021-08-13 — — CN disclosed
CN-112375015-A Preparation method of di-tert-butyloxycarbonylaminoacetic acid 安徽昊帆生物有限公司 2021-02-19 — — CN disclosed
US-20100197573-A1 Transglutaminase Mediated Conjugation of Growth Hormone NOVO NORDISK HEALTH CARE AG (CH) 2010-08-05 — — US disclosed
US-20100197573-A1 Transglutaminase Mediated Conjugation of Growth Hormone NOVO NORDISK HEALTH CARE AG (CH) 2010-08-05 — — US disclosed
US-20100197573-A1 Transglutaminase Mediated Conjugation of Growth Hormone NOVO NORDISK HEALTH CARE AG (CH) 2010-08-05 — — US disclosed
EP-2203471-A2 IMMUNOMODULATORY PEPTIDES SYNTONIX PHARMACEUTICALS, INC. (US) 2010-07-07 — — EP disclosed
US-20100159446-A1 Detection Assays and Use Thereof ENSEMBLE THERAPEUTICS CORPORATION 2010-06-24 — — US disclosed
US-20100143258-A1 TUMOR MARGIN IMAGING AGENTS GENERAL ELECTRIC COMPANY (US) 2010-06-10 — — US disclosed
WO-2009020867-A2 IMMUNOMODULATORY PEPTIDES SYNTONIX PHARMACEUTICALS, INC. (US) 2009-02-12 — — WO disclosed
EP-1893239-A2 TRANSGLUTAMINASE MEDIATED CONJUGATION OF GROWTH HORMONE Novo Nordisk Health Care AG (CH) 2008-03-05 — — EP disclosed
WO-2006134148-A2 TRANSGLUTAMINASE MEDIATED CONJUGATION OF GROWTH HORMONE NOVO NORDISK HEALTH CARE AG (DK) 2006-12-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100143258-A1 TUMOR MARGIN IMAGING AGENTS TPD52L2, LGALS4, TRIM4 HDAC6 1217/4885HDAC1 800/4885HDAC2 1945/4885
US-20230355737-A1 PARTICLE COMPRISING AN RSV-F PROTEIN FOR USE IN RSV VACCINATION CUTA, RRP12, VAC14 HDAC6 975/4885HDAC1 3215/4885HDAC2 2607/4885
US-20100197573-A1 Transglutaminase Mediated Conjugation of Growth Hormone TGM2, GHITM, GHRHR HDAC6 1829/4885HDAC1 1892/4885HDAC2 2859/4885
US-20230173092-A1 ANTIBODY-DRUG CONJUGATES CD44, CD47, FCGR3B HDAC6 62/4885HDAC1 1884/4885HDAC2 1941/4885
US-20250041439-A1 ANTIBODY-DRUG CONJUGATES CD44, CD47, FCGR3B HDAC6 62/4885HDAC1 1884/4885HDAC2 1941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.