Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL926249 | 0.93 | TRPM8 (0.49) | TRPM8AKT1P2RX4TRPV1TYK2 | |
| SCHEMBL29532603 | 0.93 | TRPM8 (0.49) | TRPM8AKT1P2RX4TRPV1TYK2 | |
| SCHEMBL28586168 | 0.82 | TRPV1 (0.35) | TRPM8TRPV1CYP19A1 | |
| SCHEMBL28586171 | 0.76 | TRPM8 (0.42) | TRPM8TRPV1CYP19A1EPHX1 | |
| SCHEMBL926043 | 0.72 | TRPM8 (0.57) | TRPM8P2RX4TRPV1CYP19A1EPHX1 | |
| SCHEMBL23951519 | 0.69 | ROCK2 (0.47) | AKT1 | |
| Hydrochloric Acid SCHEMBL23924428 | 0.68 | ROCK2 (0.46) | AKT1 | |
| Hydrochloric Acid SCHEMBL23924426 | 0.68 | ROCK2 (0.46) | AKT1 | |
| Hydrochloric Acid SCHEMBL28932983 | 0.68 | ROCK2 (0.46) | AKT1 | |
| SCHEMBL2628761 | 0.68 | TRPM8 (0.58) | TRPM8P2RX4EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803948-B | Warming sensation compound | 高砂香料工业株式会社 | 2022-03-01 | — | — | CN | claimed |
| US-20230050077-A1 | COMPOSITIONS AND METHODS FOR TREATING HOT FLASHES | THE PROCTER & GAMBLE COMPANY | 2023-02-16 | — | — | US | disclosed |
| CN-109803948-B | Warming sensation compound | 高砂香料工业株式会社 | 2022-03-01 | — | — | CN | disclosed |
| US-20210315784-A1 | Structured Rheological Solid Compositions | THE PROCTER & GAMBLE COMPANY | 2021-10-14 | — | — | US | disclosed |
| CN-111432842-A | Non-pharmaceutical teething cooling composition | 丘奇和德怀特有限公司 | 2020-07-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230050077-A1 | COMPOSITIONS AND METHODS FOR TREATING HOT FLASHES | ELOVL5, ELOVL3, HCN3 | TRPM8 672/4885AKT1 4216/4885P2RX4 1989/4885 |
| US-20210315784-A1 | Structured Rheological Solid Compositions | RCC1, CWC27, RBM17 | TRPM8 4362/4885AKT1 834/4885P2RX4 4678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.