SCHEMBL23913703

SCHEMBL23913703

CS(C)(c1cccc(Br)c1)c1cccc(Br)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
MAPK1 P28482 1/20 0.48
HSD17B2 P37059 1/20 0.40
ATM Q13315 1/20 0.40
EDNRB P24530 2/20 0.39
EDNRA P25101 2/20 0.39
MMP2 P08253 2/20 0.39
PGR P06401 1/20 0.38
MBTD1 Q05BQ5 1/20 0.37
L3MBTL3 Q96JM7 1/20 0.37
BRD4 O60885 1/20 0.37
WDR5 P61964 1/20 0.37
TAAR1 Q96RJ0 2/20 0.36
MAP4K4 O95819 1/20 0.36
PAK4 O96013 1/20 0.36
PIM1 P11309 1/20 0.36
LTK P29376 1/20 0.36
KDR P35968 1/20 0.36
MAPK14 Q16539 1/20 0.36
LRRK2 Q5S007 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25390073 0.81 ALDH1A1 (0.44) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL265696 0.81 PTGS2 (0.46) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL29595880 0.81 PTGS2 (0.46) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL23914033 0.79 ALDH1A1 (0.43) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL18640198 0.78 HSD17B2 (0.43) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL8431610 0.76 PGR (0.43) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL3679487 0.75 LMNA (0.54) ALDH1A1HSD17B2ATMEDNRBEDNRA
SCHEMBL31668877 0.75 LMNA (0.54) ALDH1A1HSD17B2ATMEDNRBEDNRA
SCHEMBL19406196 0.75 ALDH1A1 (0.42) ALDH1A1MAPK1HSD17B2ATMEDNRB
SCHEMBL31391247 0.75 LMNA (0.54) ALDH1A1HSD17B2ATMEDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME LG CHEM, LTD. (KR) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317147-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME CYP1A1, CRY1, CYP1B1 ALDH1A1 23/4885MAPK1 813/4885HSD17B2 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.