Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.43 |
| ▸ | P2RY10 | O00398 | 7/20 | 0.42 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.40 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.40 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757135 | 0.84 | DGKA (0.52) | LPAR1LPAR4LPAR2LPAR3DGKA | |
| SCHEMBL3917799 | 0.76 | DGKA (0.53) | LPAR1LPAR4LPAR2LPAR3DGKA | |
| SCHEMBL28261297 | 0.76 | DGKA (0.53) | LPAR1LPAR4LPAR2LPAR3DGKA | |
| SCHEMBL4817492 | 0.76 | FABP3 (0.56) | LPAR1LPAR4LPAR2LPAR3MAPT | |
| SCHEMBL2482147 | 0.75 | DGKA (0.50) | P2RY10GPR34GPR174DGKAMAPT | |
| SCHEMBL15648440 | 0.75 | DGKA (0.50) | P2RY10GPR34GPR174DGKAMAPT | |
| SCHEMBL6927476 | 0.75 | DGKA (0.50) | P2RY10GPR34GPR174DGKAMAPT | |
| SCHEMBL192213 | 0.75 | DGKA (0.50) | P2RY10GPR34GPR174DGKAMAPT | |
| SCHEMBL318615 | 0.75 | DGKA (0.50) | P2RY10GPR34GPR174DGKAMAPT | |
| SCHEMBL346381 | 0.75 | DGKA (0.50) | P2RY10GPR34GPR174DGKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4138772-A1 | ENVIRONMENTALLY FRIENDLY COSMETIC SUNSCREEN | Beiersdorf AG (DE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021213753-A1 | ENVIRONMENTALLY FRIENDLY COSMETIC SUNSCREEN | BEIERSDORF AG (DE) | 2021-10-28 | — | — | WO | disclosed |