⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191042 | 0.79 | TGM2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL18191032 | 0.75 | HRH3 (0.44) | — | |
| SCHEMBL23935916 | 0.75 | METAP2 (0.42) | — | |
| SCHEMBL23935877 | 0.75 | METAP2 (0.42) | — | |
| SCHEMBL18190981 | 0.75 | MTOR (0.39) | — | |
| SCHEMBL18197822 | 0.74 | SCN5A (0.43) | — | |
| SCHEMBL18191040 | 0.74 | P2RX7 (0.31) | — | |
| Hydrochloric Acid SCHEMBL18190999 | 0.73 | SCN5A (0.42) | — | |
| Acetic Acid SCHEMBL18190974 | 0.73 | FPR2 (0.40) | — | |
| SCHEMBL18197800 | 0.72 | MTOR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288918-B1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC (US) | 2021-10-20 | — | — | EP | disclosed |