Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 9/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011636 | 0.93 | ADAM17 (0.46) | ADAM17LMNAALDH1A1HSD17B10HRH3 | |
| SCHEMBL24011363 | 0.91 | LMNA (0.54) | ADAM17LMNAALDH1A1HRH3OPRM1 | |
| SCHEMBL24011472 | 0.84 | NPC1 (0.58) | ADAM17ALDH1A1HSD17B10RAB9APPID | |
| SCHEMBL24011556 | 0.81 | ACHE (0.49) | ALDH1A1 | |
| SCHEMBL24011560 | 0.78 | NPC1 (0.57) | LMNAALDH1A1RAB9APPIDHRH3 | |
| SCHEMBL24011270 | 0.78 | PKM (0.45) | LMNAALDH1A1HRH3 | |
| SCHEMBL24011567 | 0.78 | PKM (0.43) | LMNAALDH1A1RAB9A | |
| SCHEMBL24011598 | 0.78 | SMN1; SMN2 (0.57) | ADAM17LMNAALDH1A1HSD17B10RAB9A | |
| SCHEMBL24011343 | 0.77 | LMNA (0.55) | ADAM17LMNAALDH1A1RAB9AHRH3 | |
| SCHEMBL26633877 | 0.76 | NPC1 (0.53) | ADAM17ALDH1A1HSD17B10RAB9APPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |