Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24011321 | 0.86 | MCHR1 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24011556 | 0.82 | ACHE (0.49) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL24011270 | 0.80 | PKM (0.45) | ALDH1A1KDM4EMTNR1BL3MBTL1 | |
| SCHEMBL24011567 | 0.79 | PKM (0.43) | SMN1; SMN2ALDH1A1KDM4EMTNR1BPOLB | |
| SCHEMBL26633908 | 0.78 | MCHR1 (0.47) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL24011413 | 0.75 | PKM (0.39) | KMT2ASMN1; SMN2ALDH1A1KDM4EMMP1 | |
| SCHEMBL24011251 | 0.74 | ADAM17 (0.47) | ALDH1A1OPRM1 | |
| SCHEMBL24011636 | 0.74 | ADAM17 (0.46) | MEN1KMT2AALDH1A1OPRM1 | |
| SCHEMBL24011363 | 0.73 | LMNA (0.54) | KMT2AALDH1A1KDM4EOPRM1L3MBTL1 | |
| SCHEMBL24011320 | 0.73 | MCHR1 (0.61) | SMN1; SMN2KDM4EMTNR1BCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |