Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.41 |
| ▸ | GOT1 | P17174 | 1/20 | 0.41 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.41 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3253419 | 0.78 | MAOA (0.42) | NPC1MITFRAB9ASIGMAR1SMN1; SMN2 | |
| SCHEMBL5527249 | 0.76 | AADAT (0.42) | AADATGOT1KYAT1KYAT3NPC1 | |
| SCHEMBL11792985 | 0.73 | MTNR1A (0.38) | NPC1MITFRAB9APOLBSMN1; SMN2 | |
| SCHEMBL13826481 | 0.70 | MEN1 (0.48) | AADATGOT1KYAT1KYAT3NPC1 | |
| SCHEMBL7757572 | 0.70 | AADAT (0.47) | AADATGOT1KYAT1KYAT3RAB9A | |
| SCHEMBL14313917 | 0.70 | AADAT (0.37) | AADATGOT1KYAT1KYAT3NPC1 | |
| SCHEMBL3195836 | 0.64 | RNASEH1 (0.60) | AADATGOT1KYAT1KYAT3POLB | |
| SCHEMBL29836002 | 0.64 | RNASEH1 (0.60) | AADATGOT1KYAT1KYAT3POLB | |
| SCHEMBL553792 | 0.64 | NPC1 (0.35) | AADATGOT1KYAT1KYAT3NPC1 | |
| SCHEMBL5375189 | 0.62 | NPC1 (0.34) | AADATGOT1KYAT1KYAT3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352876-B1 | TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS | BASF SE (DE) | 2012-12-12 | — | — | EP | claimed |
| US-20110217348-A1 | TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS | BASF SE (DE) | 2011-09-08 | — | — | US | claimed |
| US-20030162809-A1 | Use of dihydroxyquinoline to aid in increasing milk production and feed utilization | SOLUTIA, INC. (US) | 2003-08-28 | — | — | US | claimed |
| EP-0998193-B1 | USE OF DIHYDROXYQUINOLINE COMPOUNDS TO EXTEND THE SHELF LIFE OF PRODUCTS OF MAMMALS AND FISH | SOLUTIA INC (US) | 2003-01-29 | — | — | EP | claimed |
| EP-2352876-B1 | TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS | BASF SE (DE) | 2012-12-12 | — | — | EP | disclosed |
| US-20110217348-A1 | TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS | BASF SE (DE) | 2011-09-08 | — | — | US | disclosed |
| JP-2008143890-A | NEW 1,2-DIHYDROXYQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLAMINO LOWER ALKYL GROUP AND ESTER STRUCTURE-INTRODUCED PHENYL GROUP AS SUBSTITUENT | SANTEN PHARMACEUT CO LTD | 2008-06-26 | — | — | JP | disclosed |
| JP-2008143889-A | NEW 1,2-DIHYDROXYQUINOLINE DERIVATIVE HAVING SUBSTITUTED PHENYLCHALCOGENO LOWER ALKYL GROUP AND ESTER STRUCTURE-INTRODUCED PHENYL GROUP AS SUBSTITUENT | SANTEN PHARMACEUT CO LTD | 2008-06-26 | — | — | JP | disclosed |
| JP-2008143891-A | NEW 1,2-DIHYDROXYQUINOLINE DERIVATIVE HAVING (SUBSTITUTED PHENYL OR SUBSTITUTED HETEROCYCLIC)CARBONYLOXY LOWER ALKYL GROUP AND ESTER STRUCTURE-INTRODUCED PHENYL GROUP AS SUBSTITUENT | SANTEN PHARMACEUT CO LTD | 2008-06-26 | — | — | JP | disclosed |
| EP-0752872-A4 | NADH OXIDASE AS A TARGET IN DIAGNOSIS AND THERAPY | MORRE D JAMES (US) | 2005-01-19 | — | — | EP | disclosed |
| US-20030162809-A1 | Use of dihydroxyquinoline to aid in increasing milk production and feed utilization | SOLUTIA, INC. (US) | 2003-08-28 | — | — | US | disclosed |
| US-20030162809-A1 | Use of dihydroxyquinoline to aid in increasing milk production and feed utilization | SOLUTIA, INC. (US) | 2003-08-28 | — | — | US | disclosed |
| EP-0998193-B1 | USE OF DIHYDROXYQUINOLINE COMPOUNDS TO EXTEND THE SHELF LIFE OF PRODUCTS OF MAMMALS AND FISH | SOLUTIA INC (US) | 2003-01-29 | — | — | EP | disclosed |
| EP-0998193-A4 | USE OF DIHYDROXYQUINOLINE COMPOUNDS TO EXTEND THE SHELF LIFE OF PRODUCTS OF MAMMALS AND FISH | SOLUTIA INC (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0998193-A1 | USE OF DIHYDROXYQUINOLINE COMPOUNDS TO EXTEND THE SHELF LIFE OF PRODUCTS OF MAMMALS AND FISH | Solutia Inc. (US) | 2000-05-10 | — | — | EP | disclosed |
| WO-1999016441-A1 | APORPHINOID MATRIX METALLOPROTEINASE INHIBITORS | ROCHE DIAGNOSTICS GMBH (DE) | 1999-04-08 | — | — | WO | disclosed |
| WO-1999004624-A1 | USE OF DIHYDROXYQUINOLINE COMPOUNDS TO EXTEND THE SHELF LIFE OF PRODUCTS OF MAMMALS AND FISH | SOLUTIA INC. (US) | 1999-02-04 | — | — | WO | disclosed |
| EP-0752872-A1 | NADH OXIDASE AS A TARGET IN DIAGNOSIS AND THERAPY | Portola Sciences, Inc. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026743-A1 | NADH OXIDASE AS A TARGET IN DIAGNOSIS AND THERAPY | PORTOLA SCIENCES, INC. (US) | 1995-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162809-A1 | Use of dihydroxyquinoline to aid in increasing milk production and feed utilization | NDUFB5, NQO2, DBH | AADAT 48/4885GOT1 734/4885KYAT1 3178/4885 |
| US-20110217348-A1 | TREATED TEXTILE MATERIAL FOR USE IN AQUATIC ENVIRONMENTS | C9, ADORA2B, C5 | AADAT 343/4885GOT1 2415/4885KYAT1 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.