Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 3/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26309093 | 0.76 | BCHE (0.41) | MAPTHSD17B10ATMSMN1; SMN2DPP4 | |
| SCHEMBL3566677 | 0.76 | KMT2A (0.44) | MAPTJAK1JAK2JAK3HSD17B10 | |
| SCHEMBL12312920 | 0.75 | MTNR1A (0.36) | HSD17B10ATMSMN1; SMN2MEN1CYP2C19 | |
| SCHEMBL12312726 | 0.75 | EPHX2 (0.41) | HSD17B10ATMSMN1; SMN2TSHRCHRNB2 | |
| SCHEMBL21569667 | 0.74 | LMNA (0.40) | HSD17B10MEN1KMT2ANAAA | |
| SCHEMBL6183015 | 0.73 | CTSB (0.50) | MAPTJAK1JAK2JAK3HSD17B10 | |
| SCHEMBL21806279 | 0.73 | CHRNB2 (0.42) | MAPTJAK1JAK2JAK3HSD17B10 | |
| SCHEMBL14126571 | 0.73 | ATM (0.35) | MAPTHSD17B10ATMSMN1; SMN2TSHR | |
| SCHEMBL3456296 | 0.71 | NAAA (0.53) | MAPTJAK1JAK2JAK3HSD17B10 | |
| SCHEMBL20994692 | 0.70 | ATM (0.42) | HSD17B10ATMSMN1; SMN2DPP4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355115-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2021-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210355115-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS AND USES THEREOF | SLC26A4, ALDH5A1, SLC8B1 | MAPT 3010/4885JAK1 2522/4885JAK2 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.