Sugi Predict

Sugi Predict / Compounds / SCHEMBL24045930

SCHEMBL24045930

SCHEMBL24045930

c1ccc(CN(Cc2ccccc2)OCC2CCCCC2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ G6PC1 P35575 1/20 0.44
▸ SLC18A3 Q16572 1/20 0.41
▸ ATM Q13315 1/20 0.40
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ OPRK1 P41145 1/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ SIGMAR1 Q99720 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ EPHX2 P34913 1/20 0.38
▸ AGER Q15109 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8496296 0.76 OPRM1 (0.44) G6PC1SLC18A3ATMOPRM1OPRD1
SCHEMBL825821 0.74 TDP1 (0.50) MEN1ALDH1A1KMT2A
SCHEMBL5722096 0.73 OPRM1 (0.61) G6PC1OPRM1OPRD1OPRK1KDM4E
SCHEMBL2701945 0.73 CTSL (0.53) —
SCHEMBL11115148 0.72 SLC6A2 (0.56) G6PC1SLC18A3KDM4EMEN1ALDH1A1
SCHEMBL10709827 0.72 SLC6A2 (0.56) G6PC1SLC18A3KDM4EMEN1ALDH1A1
Hydrochloric Acid SCHEMBL30384626 0.71 CTSL (0.51) —
SCHEMBL4677170 0.71 TSHR (0.54) —
SCHEMBL522763 0.70 SLC18A3 (0.49) G6PC1SLC18A3ATMOPRM1OPRD1
SCHEMBL8356587 0.69 VCP (0.40) ALDH1A1ALOX12HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912647-B2 Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-02-27 — — US disclosed
US-11912647-B2 Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2024-02-27 — — US disclosed
US-20210363098-A1 DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2021-11-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210363098-A1 DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION ADH5, ADH1A, NAT1 G6PC1 3152/4885SLC18A3 1127/4885ATM 2220/4885
US-11912647-B2 Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation ADH5, ADH1A, NAT1 G6PC1 3148/4885SLC18A3 1159/4885ATM 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.