SCHEMBL2412493

SCHEMBL2412493

CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)C(F)C(=O)C(F)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1

nearest known ligand 0.69

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 12/20 0.69
▸ CAPN1 P07384 2/20 0.66
▸ CTSL P07711 6/20 0.65
▸ CTSB P07858 4/20 0.65
▸ CTSS P25774 3/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2409535 0.91 CAPN1 (0.66) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL4325080 0.90 CTSK (0.62) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL14148467 0.87 CTSK (0.77) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL2930262 0.87 CTSK (0.77) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL20770085 0.87 CTSK (0.77) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL25406813 0.87 CTSK (0.77) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL8823918 0.87 CTSK (0.77) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL4872585 0.87 CTSK (0.77) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL20759712 0.86 CTSK (0.76) CTSKCAPN1CTSLCTSBCTSS
SCHEMBL20741007 0.86 CTSK (0.76) CTSKCAPN1CTSLCTSBCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157152-A Compositions and methods for improving the efficacy of a drug 赫利昂生物股份有限公司 2023-05-23 — — CN claimed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 — — EP claimed
WO-2021231872-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG HEALION BIO, INC. (US) 2021-11-18 — — WO claimed
US-8232240-B2 Inhibitors of enveloped virus infectivity THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2012-07-31 — — US claimed
US-20090053263-A1 Inhibitors of Enveloped Virus Infectivity THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2009-02-26 — — US claimed
US-20080139458-A1 Lubricating a joint in a mammal by administering lubricin and an enzyme inhibitor like Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) MUCOSAL THERAPEUTICS 2008-06-12 — — US claimed
WO-2006091610-A2 INHIBITORS OF ENVELOPED VIRUS INFECTIVITY THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2006-08-31 — — WO claimed
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics UNIV CHICAGO (US) 2024-01-04 — — US disclosed
US-20230257698-A1 FETAL TROPHOBLAST COMPOSITIONS AND METHODS NEXTGEN JANE, INC. 2023-08-17 — — US disclosed
CN-116157152-A Compositions and methods for improving the efficacy of a drug 赫利昂生物股份有限公司 2023-05-23 — — CN disclosed
EP-4179117-A1 FETAL TROPHOBLAST COMPOSITIONS AND METHODS NextGen Jane, Inc. (US) 2023-05-17 — — EP disclosed
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 — — US disclosed
CN-115768351-A Fluid characterization method 新生代吉恩公司 2023-03-07 — — CN disclosed
EP-1827478-A2 METHODS OF TREATMENT FOR INJURED OR DISEASED JOINTS Mucosal Therapeutics LLC (US) 2007-09-05 — — EP disclosed
US-20070203073-A1 SARS and Ebola inhibitors and use thereof, and methods for their discovery DIAMOND SCOTT L 2007-08-30 — — US disclosed
US-20070197438-A1 Dynamin mediated diseases and associated methods and products THE GENERAL HOSPITAL CORPORATION (US) 2007-08-23 — — US disclosed
US-20060142546-A1 Immunogenic muc1 glycopeptides UNIVERSITAT ZU KOLN (DE) 2006-06-29 — — US disclosed
WO-2006060473-A2 METHODS OF TREATMENT OF INJURED OR DISEASED JOINTS WITH LUBRICIN COMPOSITIONS MUCOSAL THERAPEUTICS LLC (US) 2006-06-08 — — WO disclosed
EP-1537143-A2 IMMUNOGENIC MUC1 GLYCOPEPTIDES Cell Center Cologne GmbH (DE) 2005-06-08 — — EP disclosed
WO-2004022590-A2 IMMUNOGENIC MUC1 GLYCOPEPTIDES CELL CENTER COLOGNE GMBH (DE) 2004-03-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES CTSV, CTSB, CTSS CTSK 11/4885CAPN1 226/4885CTSL 13/4885
US-20060142546-A1 Immunogenic muc1 glycopeptides MUC1, TP53, LGALS3BP CTSK 558/4885CAPN1 649/4885CTSL 958/4885
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics NSUN2, NSUN3, POLRMT CTSK 679/4885CAPN1 632/4885CTSL 370/4885
US-20070203073-A1 SARS and Ebola inhibitors and use thereof, and methods for their discovery CTSL, CTSV, CTSZ CTSK 10/4885CAPN1 253/4885CTSL 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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