Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.40 |
| ▸ | PARG | Q86W56 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151592 | 0.80 | CDK2 (0.43) | SRCCDK2TLK2KDR | |
| SCHEMBL24152341 | 0.79 | NPC1 (0.46) | TLK2HPGDGAA | |
| SCHEMBL24152889 | 0.79 | CASP3 (0.59) | ALDH1A1TSHRGAA | |
| SCHEMBL24151583 | 0.77 | CDK2 (0.42) | SRCCDK2TLK2ALDH1A1KDR | |
| SCHEMBL24152849 | 0.77 | MGAT2 (0.49) | MGAT2SRCCDK2ALDH1A1MAPK1 | |
| SCHEMBL24151582 | 0.77 | PDPK1 (0.43) | MGAT2SRCCDK2TLK2BRD4 | |
| SCHEMBL24152392 | 0.77 | MOGAT2 (0.45) | MGAT2CDK2ALDH1A1 | |
| SCHEMBL24152477 | 0.76 | SYK (0.49) | MGAT2SRCCDK2SMN1; SMN2KDM4E | |
| SCHEMBL24152474 | 0.76 | CDK2 (0.45) | SRCCDK2ALDH1A1KDR | |
| SCHEMBL24151550 | 0.76 | GAA (0.52) | MGAT2TLK2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |