Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dibenzoylmethane SCHEMBL7100268 | 0.92 | IDO1 (0.47) | IDO1TDO2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4784600 | 0.77 | IDO1 (0.57) | IDO1TDO2CYP1A2CYP2C19RAB9A | |
| SCHEMBL10664130 | 0.74 | KMT2A (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL24181250 | 0.72 | VCP (0.46) | IDO1TDO2MAOBMAOANPC1 | |
| SCHEMBL7913686 | 0.71 | KMT2A (0.54) | CYP1A2CYP3A4CYP2C9CYP2C19HIF1A | |
| SCHEMBL7752908 | 0.70 | HPGD (0.58) | IDO1TDO2CYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL2394174 | 0.70 | DPEP1 (0.49) | MAOBMAOANPC1RAB9ATDP1 | |
| SCHEMBL1907796 | 0.70 | DPEP1 (0.49) | MAOBMAOANPC1RAB9ATDP1 | |
| SCHEMBL7583346 | 0.70 | NPC1 (0.40) | ALDH1A1KMT2AMAPTMAOBMAOA | |
| SCHEMBL7583350 | 0.70 | NPC1 (0.40) | ALDH1A1KMT2AMAPTMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | ABBOTT LABORATORIES | 2002-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099070-A1 | Dihydronaphthyridine potassium channel openers | KCNH1, KCNN1, KCNJ2 | IDO1 3818/4885TDO2 3356/4885CYP1A2 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.