Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260597 | 1.00 | PDK1 (0.58) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL6515359 | 0.90 | PDK1 (0.47) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL2061507 | 0.89 | PDK1 (0.46) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL6953347 | 0.89 | PDK1 (0.46) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL7443550 | 0.87 | VCAM1 (0.46) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL6886014 | 0.85 | ALDH1A1 (0.46) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL5957173 | 0.85 | PDGFRB (0.55) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL11247732 | 0.85 | CASP6 (0.57) | VCAM1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7450087 | 0.84 | PDK1 (0.42) | PDK1VCAM1KMT2AALDH1A1MAPT | |
| SCHEMBL7443631 | 0.84 | VCAM1 (0.44) | PDK1VCAM1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889999-B | Ion labeling for oligoribonucleotide synthesis | 皇家学习促进学会/麦吉尔大学 | 2021-06-01 | — | — | CN | disclosed |
| US-9920084-B2 | Ionic tags for synthesis of oligoribonucleotides | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2018-03-20 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | HONG KONG POLYTECHNIC UNIVERSITY (HK) | 2014-09-11 | — | — | US | disclosed |
| US-8445734-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-8445734-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-8445734-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| WO-2013026142-A1 | IONIC TAGS FOR SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2013-02-28 | — | — | WO | disclosed |
| WO-2012024776-A1 | BLOCK SYNTHESIS OF OLIGORIBONUCLEOTIDES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-03-01 | — | — | WO | disclosed |
| US-20100292458-A1 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20100292458-A1 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
| US-7759513-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| US-7759513-B2 | Photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2010-07-20 | — | — | US | disclosed |
| WO-2004089529-A1 | METHOD FOR THE INTRAMOLECULAR ENERGY TRANSFER FOR THE CLEAVAGE OF LABILE FUNCTIONAL GROUP FROM BIOMOLECULES AND THE PROTECTED BIOMOLECULES | Universität Konstanz (DE) | 2004-10-21 | — | — | WO | disclosed |
| US-20040175741-A1 | Novel photolabile protective groups for improved processes to prepare oligonucleotide arrays | NIGU CHEMIE GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| WO-2004074300-A2 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NIGU CHEMIE GMBH (DE) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292458-A1 | NOVEL PHOTOLABILE PROTECTIVE GROUPS FOR IMPROVED PROCESSES TO PREPARE OLIGONUCLEOTIDE ARRAYS | NT5C3B, NSUN2, ERCC4 | PDK1 4013/4885VCAM1 3546/4885KMT2A 2382/4885 |
| US-20140256926-A1 | Ionic Tags for Synthesis of Oligoribonucleotides | RNGTT, OSTC, OSGEP | PDK1 4196/4885VCAM1 3167/4885KMT2A 3196/4885 |
| US-20040175741-A1 | Novel photolabile protective groups for improved processes to prepare oligonucleotide arrays | NT5C3B, NSUN2, DCLRE1B | PDK1 3890/4885VCAM1 3745/4885KMT2A 2530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.