SCHEMBL2428985

SCHEMBL2428985

C=CC(=O)N(Cc1ccccc1)c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BCL2A1 Q16548 3/20 0.50
GSTO1 P78417 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.45
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 1/20 0.43
CFTR P13569 1/20 0.42
TRPM8 Q7Z2W7 2/20 0.40
SIGMAR1 Q99720 1/20 0.40
MMP9 P14780 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547586 0.81 L3MBTL1 (0.48) L3MBTL1ALDH1A1CFTRTRPM8SIGMAR1
SCHEMBL11220240 0.78 RAB9A (0.60) L3MBTL1ALDH1A1KMT2ACFTRTRPM8
SCHEMBL11663103 0.78 ALDH1A1 (0.49) L3MBTL1ALDH1A1KMT2ASIGMAR1MMP9
SCHEMBL27847921 0.77 TRPM8 (0.64) BCL2A1GSTO1ALDH1A1TRPM8
SCHEMBL21337993 0.75 L3MBTL1 (0.49) L3MBTL1ALDH1A1KMT2ATRPM8SIGMAR1
SCHEMBL29208602 0.75 BCL2A1 (0.48) BCL2A1GSTO1TRPM8
SCHEMBL21392983 0.75 RXRB (0.52) BCL2A1GSTO1TRPM8
SCHEMBL2799227 0.75 SIGMAR1 (0.54) ALDH1A1KMT2ATRPM8SIGMAR1
SCHEMBL4085244 0.74 SIGMAR1 (0.59) ALDH1A1KMT2ASIGMAR1
SCHEMBL31092738 0.74 BCL2A1 (0.47) BCL2A1GSTO1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7763268-B2 Load bearing hydrogel implants THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2010-07-27 US claimed
US-20100029789-A1 Load Bearing Hydrogel Implants THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2010-02-04 US claimed
US-12613233-B2 Threshold-triggered tracer particles PATENTPOOL INNOVATIONS MANAGEMENT GMBH (DE) 2026-04-28 US disclosed
EP-4394022-B1 SUBSTRATE COMPRISING A SURFACE COATED WITH AN EPILAME AGENT AND METHOD FOR DEPILATING SUCH A SUBSTRATE SWATCH GROUP RES & DEV LTD (CH) 2026-02-18 EP disclosed
EP-4394020-B1 SUBSTRATE COMPRISING A SURFACE COATED WITH AN EPILAME AGENT AND METHOD FOR EPIMERISING SUCH A SUBSTRATE SWATCH GROUP RES & DEV LTD (CH) 2025-07-16 EP disclosed
US-20240228796-A1 SUBSTRATE COMPRISING A SURFACE COVERED WITH AN EPILAME AGENT AND METHOD FOR EPILAME-COATING SUCH A SUBSTRATE THE SWATCH GROUP RESEARCH AND DEVELOPMENT LTD (CH) 2024-07-11 US disclosed
WO-2024141565-A1 SUBSTRATE COMPRISING A SURFACE COVERED WITH AN EPILAME AGENT AND METHOD FOR COATING SUCH A SUBSTRATE WITH EPILAME THE SWATCH GROUP RESEARCH AND DEVELOPMENT LTD (CH) 2024-07-04 WO disclosed
EP-4394020-A1 SUBSTRATE COMPRISING A SURFACE COATED WITH AN EPILAME AGENT AND METHOD FOR EPIMERISING SUCH A SUBSTRATE The Swatch Group Research and Development Ltd (CH) 2024-07-03 EP disclosed
EP-4394021-A1 SUBSTRATE COMPRISING A SURFACE COATED WITH AN EPILAME AGENT AND METHOD FOR EPILAMING SUCH A SUBSTRATE The Swatch Group Research and Development Ltd (CH) 2024-07-03 EP disclosed
EP-3786415-B1 THRESHOLD-TRIGGERED TRACER PARTICLES PATENTPOOL INNOVATIONS MAN GMBH (DE) 2024-07-03 EP disclosed
EP-4394022-A1 SUBSTRATE COMPRISING A SURFACE COATED WITH AN EPILAME AGENT AND METHOD FOR DEPILATING SUCH A SUBSTRATE The Swatch Group Research and Development Ltd (CH) 2024-07-03 EP disclosed
US-8917018-B2 Nanomatrix separation of chromophores and uses thereof in luminescent devices RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-12-23 US disclosed
US-20110215716-A1 NANOMATRIX SEPARATION OF CHROMOPHORES AND USES THEREOF IN LUMINESCENT DEVICES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-09-08 US disclosed
US-7763268-B2 Load bearing hydrogel implants THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2010-07-27 US disclosed
US-20100029789-A1 Load Bearing Hydrogel Implants THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2010-02-04 US disclosed
EP-1809284-A4 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT MERCK & CO INC (US) 2009-09-09 EP disclosed
US-20070299101-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment MERCK SHARP & DOHME CORP. 2007-12-27 US disclosed
CN-101056635-A Niacin receptor agonists, compositions containing such compounds and methods of treatment MERCK & CO INC (US) 2007-10-17 CN disclosed
EP-1809284-A2 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT Merck & Co., Inc. (US) 2007-07-25 EP disclosed
WO-2006052555-A2 NIACIN RECEPTOR AGONISTS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT MERCK & CO., INC. (US) 2006-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299101-A1 Niacin Receptor Agonists, Compositions Containing Such Compounds and Methods of Treatment LDLR, APOB, FFAR1 BCL2A1 3487/4885GSTO1 1525/4885L3MBTL1 4782/4885
US-12613233-B2 Threshold-triggered tracer particles CD63, MYADM, TMEM63A BCL2A1 2706/4885GSTO1 2356/4885L3MBTL1 1471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.