Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20705908 | 0.90 | CASP2 (0.39) | MTNR1AMTNR1BMEN1KMT2ATSHR | |
| SCHEMBL16309339 | 0.84 | MTNR1A (0.46) | MTNR1AMTNR1BMEN1KMT2ATP53 | |
| SCHEMBL23226171 | 0.82 | TP53 (0.41) | MEN1KMT2ATP53HDAC3HDAC4 | |
| SCHEMBL23397424 | 0.81 | ALDH1A1 (0.39) | MEN1KMT2ATP53ADAM17HDAC3 | |
| SCHEMBL20118250 | 0.79 | FAAH (0.38) | MEN1KMT2ATP53ADAM17HDAC3 | |
| SCHEMBL20705909 | 0.79 | HPGD (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL12945876 | 0.79 | ALDH1A1 (0.36) | MEN1KMT2ATP53TSHRADAM17 | |
| SCHEMBL10036356 | 0.79 | ITGB3 (0.41) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL23975074 | 0.78 | ALDH1A1 (0.38) | ADAM17HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL16204453 | 0.78 | ALDH1A1 (0.38) | ADAM17HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11278628-B2 | Pharmaceutical formulations and methods of use thereof | IMMUNOGEN, INC. (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11278628-B2 | Pharmaceutical formulations and methods of use thereof | GABRA5, GABRA6, GABRA3 | MTNR1A 2263/4885MTNR1B 1972/4885MEN1 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.