Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.46 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.46 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14976729 | 0.83 | ALDH1A1 (0.49) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL16676192 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL8973769 | 0.81 | TXNRD1 (0.66) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL31453603 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL1114984 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL3712418 | 0.81 | CA2 (0.56) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL31011656 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL20494498 | 0.80 | ALDH1A1 (0.55) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL31217501 | 0.80 | TXNRD1 (0.63) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 | |
| SCHEMBL14977083 | 0.80 | ALDH1A1 (0.44) | ALDH1A1HIF1ATXNRD1TXNRD3TXNRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2377863-A1 | Piperidine GPCR agonists | Prosidion Limited (GB) | 2011-10-19 | — | — | EP | disclosed |
| EP-2114933-B1 | PIPERIDINE GPCR AGONISTS | PROSIDION LTD (GB) | 2011-09-07 | — | — | EP | disclosed |
| US-20100048632-A1 | Piperidine GPCR Agonists | PROSIDION LIMITED (GB) | 2010-02-25 | — | — | US | disclosed |
| EP-2114933-A1 | PIPERIDINE GPCR AGONISTS | Prosidion Limited (GB) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008081204-A1 | PIPERIDINE GPCR AGONISTS | PROSIDION LIMITED (GB) | 2008-07-10 | — | — | WO | disclosed |
| US-20070208032-A1 | Chemical compounds | ASTRAZENECA AB | 2007-09-06 | — | — | US | disclosed |
| US-20070208032-A1 | Chemical compounds | ASTRAZENECA AB | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048632-A1 | Piperidine GPCR Agonists | GPR119, GPR27, GLP1R | ALDH1A1 768/4885HIF1A 948/4885TXNRD1 2038/4885 |
| US-20070208032-A1 | Chemical compounds | PDHA1, ALDH5A1, PDHA2 | ALDH1A1 25/4885HIF1A 1180/4885TXNRD1 1887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.