Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28700541 | 0.83 | NOS2 (0.39) | NOS2HPGDTSHRMEN1MAPT | |
| SCHEMBL27488816 | 0.83 | ALDH1A1 (0.37) | NOS3NOS2HPGDGABRA1GABRB2 | |
| SCHEMBL4135611 | 0.81 | ALDH1A1 (0.43) | NOS3NOS2HPGDGABRA1GABRB2 | |
| SCHEMBL28141493 | 0.79 | NOS3 (0.39) | NOS3NOS2HPGDGABRA1GABRB2 | |
| SCHEMBL26339879 | 0.77 | NOS3 (0.38) | NOS3NOS2HPGDGABRA1GABRB2 | |
| SCHEMBL5195607 | 0.77 | TRPA1 (0.41) | NOS3NOS2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL23461581 | 0.77 | CYP1A2 (0.35) | GABRA1GABRB2 | |
| SCHEMBL13057531 | 0.76 | GABRA1 (0.50) | NOS3NOS2GABRA1GABRB2GAA | |
| SCHEMBL19003090 | 0.74 | SIRT1 (0.40) | NOS3NOS2HPGDGABRA1GABRB2 | |
| SCHEMBL19880547 | 0.74 | NOS3 (0.35) | NOS3NOS2GABRA1GABRB2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076975-A1 | 5- AND 6-AZAINDOLE COMPOUNDS FOR INHIBITION OF BCR-ABL TYROSINE KINASES | ENLIVEN THERAPEUTICS, INC. (US) | 2022-04-14 | — | — | WO | disclosed |