Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028800 | 0.85 | GABRA1 (0.34) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL5195607 | 0.85 | TRPA1 (0.41) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL71053 | 0.85 | ESR1 (0.43) | ALDH1A1TRPA1ESR1ESR2TSHR | |
| SCHEMBL13057531 | 0.83 | GABRA1 (0.50) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL24344144 | 0.81 | NOS3 (0.35) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL9497778 | 0.81 | NOS2 (0.44) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL27488816 | 0.81 | ALDH1A1 (0.37) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL5356606 | 0.81 | NOS3 (0.39) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL19003090 | 0.81 | SIRT1 (0.40) | ALDH1A1NOS3NOS2GABRA1GABRB2 | |
| SCHEMBL19880547 | 0.81 | NOS3 (0.35) | ALDH1A1NOS3NOS2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2021211982-A2 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | OREGON STATE UNIVERSITY (US) | 2021-10-21 | — | — | WO | disclosed |
| US-20170349563-A1 | FORMATION OF CHROMANES BASED ON INTERMOLECULAR REACTION OF ALKYNES WITH DIMETHYLFURAN IN THE PRESENCE OF GOLD(I) COMPLEXES | DSM IP ASSETS B.V. (NL) | 2017-12-07 | — | — | US | disclosed |
| US-8883379-B2 | Resist-protective film-forming composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |
| US-20130143162-A1 | RESIST-PROTECTIVE FILM-FORMING COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-06-06 | — | — | US | disclosed |
| US-7977400-B2 | polyimide, unsaturated polymerizable compound, photoinitiator; crosslinkable to form addition-condensation copolymer or polyetherimide copolymer; no imidation of polymer through high-temperature heat treatment; alkaline development; polyimide film having excellent heat resistance, strength, elongation | TORAY INDUSTRIES, INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7476476-B2 | Photosensitive resin composition, electronic component using the same, and display unit using the same | TORAY INDUSTRIES, INC. (JP) | 2009-01-13 | — | — | US | disclosed |
| US-20090011862-A1 | Golf Ball with Negative Hardness Gradient Core | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-20080115297-A1 | 2-(Amino or Substituted Amino)-5, 6-Substituted Phenol Compounds, Dyeing Compositions Containing Them, and Use Thereof | BOLTON PHILIP D | 2008-05-22 | — | — | US | disclosed |
| US-20080108723-A1 | Photosensitive Resin Composition | TORAY INDUSTRIES, INC. (JP) | 2008-05-08 | — | — | US | disclosed |
| US-7341605-B2 | 2-(Amino or substituted amino)-5, 6-substituted phenol compounds, dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-03-11 | — | — | US | disclosed |
| US-7303855-B2 | Photoresist undercoat-forming material and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080115297-A1 | 2-(Amino or Substituted Amino)-5, 6-Substituted Phenol Compounds, Dyeing Compositions Containing Them, and Use Thereof | KRT18, S100A6, S100A4 | ALDH1A1 403/4885NOS3 508/4885NOS2 388/4885 |
| US-20170349563-A1 | FORMATION OF CHROMANES BASED ON INTERMOLECULAR REACTION OF ALKYNES WITH DIMETHYLFURAN IN THE PRESENCE OF GOLD(I) COMPLEXES | CBR1, DECR1, CBR3 | ALDH1A1 91/4885NOS3 2863/4885NOS2 2528/4885 |
| US-20230117370-A1 | REGIOSELECTIVE SYNTHESIS OF SUBSTITUTED COMPOUNDS | CYP2B6, TYR, CYP2D6 | ALDH1A1 88/4885NOS3 2128/4885NOS2 2190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.