SCHEMBL244291

SCHEMBL244291

C=CCC(=C)C(=O)OC(=O)C=C

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.35
ALDH1A1 P00352 5/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL244290 0.86 ALDH1A1 (0.31) TSHRALDH1A1HSD17B10ALOX15
SCHEMBL1044324 0.82
SCHEMBL8345796 0.80 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1049922 0.80 ALOX15 (0.31) HSD17B10ALOX15
SCHEMBL19253760 0.80 TSHR (0.41) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5702719 0.78 TSHR (0.40) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28066529 0.78 HSD17B10 (0.42) TSHRALDH1A1CYP3A4HSD17B10SMN1; SMN2
SCHEMBL3954664 0.78 TSHR (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylic Acid Methyl Ester SCHEMBL28083209 0.78 ALDH1A1 (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL7167538 0.77 TSHR (0.34) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117430810-A Thermosetting polyimide resin and preparation method thereof 徐州博康信息化学品有限公司 2024-01-23 CN claimed
US-20210221112-A1 COMPOSITE PANEL JETCOAT (SHANGHAI) CO LTD, CHINA (CN) 2021-07-22 US claimed
EP-2080774-B1 POLYMERIZABLE SULFONIC ACID ONIUM SALT AND RESIN JSR CORP (JP) 2014-01-15 EP claimed
JP-2012500273-A 2012-01-05 JP claimed
CN-102131768-A Processes for producing n-alkyl (alkyl) acrylamides NALCO CO 2011-07-20 CN claimed
CN-102112214-A Functionalized thin film polyamide membranes POLYMERS CRC LTD 2011-06-29 CN claimed
EP-2334635-A2 PROCESSES FOR PRODUCING N-ALKYL (ALKYL)ACRYLAMIDES Nalco Company (US) 2011-06-22 EP claimed
US-7956142-B2 Polymerizable sulfonic acid onium salt and resin JSR CORPORATION (JP) 2011-06-07 US claimed
US-20100063232-A1 POLYMERIZABLE SULFONIC ACID ONIUM SALT AND RESIN JSR CORPORATION (JP) 2010-03-11 US claimed
US-20100048951-A1 PROCESSES FOR PRODUCING N-ALKYL (ALKYL)ACRYLAMIDES ECOLAB USA INC. 2010-02-25 US claimed
CN-1481363-A N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as polymerisation in hibitors �������⻯ѧƷ�ع����޹�˾ 2004-03-10 CN claimed
EP-1392736-A2 ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION Ciba SC Holding AG (CH) 2004-03-03 EP claimed
CN-1474835-A (Co) polymerization of vinyl chloride in presence of stable nitroxyl free radical �������⻯ѧƷ�ع����޹�˾ 2004-02-11 CN claimed
CN-1430605-A Method for synthesizing amine ethers from secondary amino oxides CIBA SC HOLDING AG (CH) 2003-07-16 CN claimed
US-6573347-B1 Enhanced rates of polymerization and enhanced monomer to polymer conversions CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-03 US claimed
US-6569940-B1 Addition polymer using free radical catalyst; process control CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-27 US claimed
WO-2002079271-A2 ACID MACROMONOMERS AND THEIR METHOD OF PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-10-10 WO claimed
CN-1319590-A 2,2,6,6, diethyl-dimethy-1-alkoxy-piperidine compound and 1-oxide CIBA SC HOLDING AG (CH) 2001-10-31 CN claimed
CN-1253954-A Heterocyclic alkoxyl amine as regulator in controlled free radical polymerization method CIBA SC HOLDING AG (CH) 2000-05-24 CN claimed
CN-1228424-A 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators CIBA SC HOLDING AG (CH) 1999-09-15 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063232-A1 POLYMERIZABLE SULFONIC ACID ONIUM SALT AND RESIN ASIC1, RER1, RPS10 TSHR 941/4885ALDH1A1 2200/4885TP53 3458/4885
US-20100048951-A1 PROCESSES FOR PRODUCING N-ALKYL (ALKYL)ACRYLAMIDES ACR, NAAA, INA TSHR 4245/4885ALDH1A1 396/4885TP53 80/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.