SCHEMBL2445444

SCHEMBL2445444

O=C1C(O)=C(c2ccccc2)C(=O)C(O)=C1c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.65
SENP1 Q9P0U3 1/20 0.65
ME2 P23368 1/20 0.54
ME1 P48163 1/20 0.54
ME3 Q16798 1/20 0.54
EGFR P00533 1/20 0.54
FGFR1 P11362 2/20 0.52
FGFR2 P21802 2/20 0.52
FGFR4 P22455 2/20 0.52
FGFR3 P22607 2/20 0.52
MAPT P10636 2/20 0.48
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
TP53 P04637 1/20 0.48
RAB9A P51151 1/20 0.48
MAPK10 P53779 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
PDE4B Q07343 1/20 0.48
MEN1 O00255 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11659194 0.90 P2RX7 (0.65) P2RX7SENP1ME2ME1ME3
SCHEMBL6339508 0.87 SENP1 (0.57) P2RX7SENP1ME2ME1ME3
SCHEMBL11820812 0.87 P2RX7 (0.53) P2RX7SENP1ME2ME1ME3
SCHEMBL10068409 0.86 P2RX7 (0.74) P2RX7SENP1FGFR1FGFR2FGFR4
SCHEMBL17430599 0.84 SENP1 (0.53) P2RX7SENP1ME2ME1ME3
SCHEMBL12280399 0.83 P2RX7 (0.69) P2RX7SENP1FGFR1FGFR2FGFR4
SCHEMBL1063908 0.82 ME2 (0.86) P2RX7SENP1ME2ME1ME3
SCHEMBL6337913 0.82 SENP1 (0.52) P2RX7SENP1ME2ME1ME3
SCHEMBL17430602 0.81 SENP1 (0.55) P2RX7SENP1ME2ME1ME3
SCHEMBL6340048 0.80 P2RX7 (0.46) P2RX7SENP1ME2ME1ME3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021050927-A2 YEAST-HYDROLYSATE COMPOSITIONS AND METHODS OF THEIR USE California Safe Soil, LLC (US) 2021-03-18 WO claimed
CN-103974715-A Stable formulations of hyaluronan degrading enzymes HALOZYME INC 2014-08-06 CN claimed
CN-101132760-A Agent and method for colouring keratin fibres PROCTER & GAMBLE (US) 2008-02-27 CN claimed
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative L'OREAL S.A. 2007-06-14 US claimed
EP-1754514-A1 Agent and method for colouring keratin fibres Wella Aktiengesellschaft (DE) 2007-02-21 EP claimed
US-20070000073-A1 Agent and method for colouring keratin fibres PROCTER & GAMBLE COMPANY, THE 2007-01-04 US claimed
WO-2006094217-A2 AGENT AND METHOD FOR COLOURING KERATIN FIBRES THE PROCTER & GAMBLE COMPANY (US) 2006-09-08 WO claimed
US-7070625-B2 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives WELLA AG (DE) 2006-07-04 US claimed
EP-1434552-A1 METHOD FOR DYEING KERATINOUS FIBRES Henkel Kommanditgesellschaft auf Aktien (DE) 2004-07-07 EP claimed
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2004-04-01 US claimed
US-6635090-B1 Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative L'OREAL, S.A. (FR) 2003-10-21 US claimed
WO-2003030841-A1 METHOD FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-0496349-B1 Coating solution for preventing adhesion of polymer scale and method for its use SHINETSU CHEMICAL CO (JP) 1996-04-10 EP claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
WO-2025202415-A1 DHODH INHIBITORS FOR USE IN THE CHRONOPHARMACOLIGICAL TREATMENT AND PREVENTION OF OBESITY AND OBESITY-RELATED METABOLIC DISORDERS Institut National de la Santé et de la Recherche Médicale (FR) 2025-10-02 WO disclosed
US-20250262155-A1 LITHE LIPOSOMES COMPRISING ABSORPTION ENHANCERS FOR ORAL DRUG DELIVERY Aspire LLC (US) 2025-08-21 US disclosed
EP-0148787-A2 Positive type photosensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-07-17 EP disclosed
US-4105839-A Method for polymerizing ethylenically unsaturated monomers in order to eliminate polymer deposition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070130702-A1 Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative KRT18, NDUFB5, NDUFB7 P2RX7 4712/4885SENP1 3302/4885ME2 329/4885
US-20040060124-A1 Agent and method for coloring keratin fibers containing 2-benzothiazolinone-hydrazone and quinone derivatives KRT18, NDUFA1, NDUFA2 P2RX7 3875/4885SENP1 4463/4885ME2 364/4885
US-20070000073-A1 Agent and method for colouring keratin fibres KRT18, CDC73, OAT P2RX7 4511/4885SENP1 4184/4885ME2 919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.