Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5131387 | 0.76 | FABP4 (0.45) | GAAKDM4ELMNAP2RX7FABP4 | |
| SCHEMBL2799903 | 0.72 | P2RX7 (0.53) | KDM4EMEN1KMT2AP2RX7 | |
| SCHEMBL2446497 | 0.70 | PTGDR2 (0.55) | KDM4EALDH1A1HPGDKMT2AALOX5 | |
| SCHEMBL11503520 | 0.70 | NR1H2 (0.38) | GAAKMT2ACNR2NR1H2NR1H3 | |
| SCHEMBL7214267 | 0.70 | ALOX5 (0.36) | MEN1KMT2ACNR2NR1H2NR1H3 | |
| SCHEMBL28222652 | 0.69 | KIF11 (0.54) | ALDH1A1NR1H2NR1H3FABP4ACHE | |
| SCHEMBL28022302 | 0.68 | FABP4 (0.46) | FABP4 | |
| SCHEMBL14932033 | 0.68 | HSD11B1 (0.41) | GAAHTTKDM4EMEN1ALDH1A1 | |
| SCHEMBL2597832 | 0.68 | FABP4 (0.53) | HTTALDH1A1LMNANR1H2NR1H3 | |
| SCHEMBL187641 | 0.67 | NFKB1 (0.47) | GAAMEN1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614418-B1 | use of(-)(3-trihalomethylphenoxy) (4-halophenyl)acetic acid derivatives for treatment of hyperuricaemia | METABOLEX INC (US) | 2011-09-14 | — | — | EP | claimed |