Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417124 | 0.84 | LMNA (0.50) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL19625786 | 0.84 | LMNA (0.50) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL1233194 | 0.81 | MEN1 (0.47) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL1742088 | 0.79 | EGLN1 (0.50) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL12206267 | 0.78 | KCNN4 (0.48) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL13293313 | 0.78 | ALDH1A1 (0.49) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL3757683 | 0.78 | NPC1 (0.52) | MEN1KMT2APTPN1NPC1RAB9A | |
| SCHEMBL25780577 | 0.78 | KDM4E (0.61) | MEN1KMT2ARAB9AHDAC1ALDH1A1 | |
| SCHEMBL28450707 | 0.77 | DGAT1 (0.51) | MEN1KMT2APTPN1CES2CES1 | |
| SCHEMBL3835902 | 0.75 | PPARG (0.52) | MEN1KMT2ANPC1RAB9AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220194930-A1 | Matrix Metalloproteinase Inhibitors and Imaging Agents, And Methods Using Same | UNIV YALE (US) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194930-A1 | Matrix Metalloproteinase Inhibitors and Imaging Agents, And Methods Using Same | MMP3, MMP1, MMP10 | MEN1 450/4885KMT2A 2836/4885PTPN1 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.