Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614686 | 0.89 | GPR84 (0.36) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL24614971 | 0.88 | PTPN1 (0.36) | PTPN1ALOX5 | |
| SCHEMBL24614804 | 0.86 | MAPT (0.34) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL24614682 | 0.86 | S1PR5 (0.36) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL24614700 | 0.86 | PTPN1 (0.35) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL17945678 | 0.84 | PTPN1 (0.37) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL24614940 | 0.82 | HSD17B1 (0.33) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL17944189 | 0.82 | ALOX5 (0.37) | PTPN1GPR84S1PR4S1PR5ALOX5 | |
| SCHEMBL24614934 | 0.81 | PTPN1 (0.35) | PTPN1ALOX5 | |
| SCHEMBL24614750 | 0.80 | PTPN1 (0.39) | PTPN1GPR84ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | PTPN1 4341/4885GPR84 3746/4885S1PR4 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.