Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TOP2A | P11388 | 3/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29766728 | 0.85 | LMNA (0.50) | HTR3AKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL2744582 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL29766836 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL28458144 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL22506561 | 0.84 | HTR3A (0.47) | HTR3AKDM4EALDH1A1TOP2ATOP2B | |
| Hydrochloric Acid SCHEMBL6004997 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1TOP2ATOP2BLMNA | |
| SCHEMBL29518174 | 0.84 | MEN1 (0.60) | HTR3AKDM4EALDH1A1TOP2ATOP2B | |
| SCHEMBL22497601 | 0.83 | HTR3A (0.46) | HTR3AKDM4EALDH1A1TOP2ATOP2B | |
| Potassium Ion SCHEMBL22497604 | 0.82 | KDM4E (0.44) | HTR3AKDM4EALDH1A1TOP2ATOP2B | |
| SCHEMBL22506761 | 0.82 | HTR3A (0.43) | HTR3AKDM4EALDH1A1TOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220076-A1 | QUINOLINE CARBOXYLATE COMPOUND AND PREPARATION METHOD AND USE THEREOF | SDHA, GLUL, PGLS | HTR3A 4114/4885KDM4E 1227/4885ALDH1A1 632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.