SCHEMBL22497601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22497629	0.90	HTR3A (0.45)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL22506765	0.89	HTR3A (0.44)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL29766728	0.89	LMNA (0.50)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL22506761	0.84	HTR3A (0.43)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL22506763	0.83	ALDH1A1 (0.47)	KDM4EALDH1A1LMNAHPGDHSD17B10
	SCHEMBL24616680	0.83	HTR3A (0.47)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL22506780	0.82	CNR2 (0.45)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL22506782	0.80	CNR2 (0.43)	HTR3AKDM4EALDH1A1LMNAHPGD
	SCHEMBL9148070	0.80	ADRB2 (0.50)	KDM4EALDH1A1LMNAHPGDHSD17B10
	SCHEMBL2744582	0.80	KDM4E (0.59)	KDM4EALDH1A1LMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.