Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24623620 | 0.87 | CYP2A6 (0.35) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL11885002 | 0.79 | KDM4E (0.44) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL24624594 | 0.78 | GPR3 (0.50) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL24623999 | 0.77 | KDM4E (0.34) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL5406439 | 0.76 | LMNA (0.42) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL24623627 | 0.76 | KDM4E (0.36) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL20120213 | 0.75 | CDC7 (0.30) | LIMK1 | |
| SCHEMBL24623616 | 0.74 | KDM4E (0.39) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL24624005 | 0.73 | KDM4E (0.34) | KDM4EHTTALDH1A1NCOA1NCOA3 | |
| SCHEMBL22373966 | 0.73 | ALDH1A1 (0.41) | KDM4EHTTALDH1A1NCOA1NCOA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223794-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND APPLICATION THEREOF | NR0B2, FPR3, NPR3 | KDM4E 3659/4885HTT 3470/4885ALDH1A1 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.