SCHEMBL2465147

SCHEMBL2465147

N#Cc1ccc(OC(=S)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.50
TSHR P16473 2/20 0.48
F2 P00734 1/20 0.47
MAOA P21397 1/20 0.42
CYP19A1 P11511 1/20 0.42
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
MMP2 P08253 1/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA6 P23280 1/20 0.40
CA14 Q9ULX7 1/20 0.40
POLB P06746 2/20 0.40
MGLL Q99685 2/20 0.40
PARP15 Q460N3 1/20 0.40
PARP10 Q53GL7 1/20 0.40
PARP2 Q9UGN5 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
USP2 O75604 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30736490 0.82 MGLL (0.46) MAOBTSHRF2CYP19A1CA2
SCHEMBL11632810 0.81 MAOB (0.47) MAOBTSHRF2MAOAMMP2
SCHEMBL2470101 0.81 LTA4H (0.45) TSHRKDM4EMAPTALDH1A1
SCHEMBL7743966 0.78 MAOB (0.47) MAOBTSHRF2MAOACYP19A1
SCHEMBL378478 0.77 CYP19A1 (0.63) MAOBTSHRMAOACYP19A1POLB
SCHEMBL10625835 0.76 CA2 (0.43) MAOBF2CYP19A1CA2CA9
SCHEMBL2466916 0.75 SMN1; SMN2 (0.54) MAOBCA2CA9CA12MGLL
SCHEMBL4814349 0.74 ALDH1A1 (0.58) F2CA2POLBPARP15PARP10
SCHEMBL1032753 0.74 PARP10 (0.59) MAOBF2POLBPARP15PARP10
SCHEMBL14823291 0.74 LMNA (0.48) TSHRSMN1; SMN2USP2KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8410303-B2 Direct conversion of phenols into amides and esters of benzoic acid The Florida State University Research Foundation, Inc. (US) 2013-04-02 US disclosed
US-8410303-B2 Direct conversion of phenols into amides and esters of benzoic acid The Florida State University Research Foundation, Inc. (US) 2013-04-02 US disclosed
US-8410303-B2 Direct conversion of phenols into amides and esters of benzoic acid The Florida State University Research Foundation, Inc. (US) 2013-04-02 US disclosed
US-20110237798-A1 DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID The Florida State University Research Foundation, Inc. (US) 2011-09-29 US disclosed
US-20110237798-A1 DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID The Florida State University Research Foundation, Inc. (US) 2011-09-29 US disclosed
US-20110237798-A1 DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID The Florida State University Research Foundation, Inc. (US) 2011-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237798-A1 DIRECT CONVERSION OF PHENOLS INTO AMIDES AND ESTERS OF BENZOIC ACID DDC, NISCH, TST MAOB 80/4885TSHR 1057/4885F2 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.