Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 3/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016019 | 0.72 | L3MBTL1 (0.50) | ALDH1A1GAAPKMPOLBCRBN | |
| SCHEMBL7016369 | 0.70 | HTR6 (0.37) | POLBCRBNTSHRMEN1KMT2A | |
| SCHEMBL886978 | 0.70 | LMNA (0.37) | CRBNMAPT | |
| SCHEMBL24672711 | 0.70 | CRBN (0.32) | CRBN | |
| SCHEMBL8743705 | 0.69 | CRBN (0.36) | CRBNMAPT | |
| SCHEMBL4956765 | 0.68 | ALDH1A1 (0.47) | ALDH1A1GAAPKMPOLBTSHR | |
| SCHEMBL11115556 | 0.68 | ALDH1A1 (0.51) | ALDH1A1GAAPOLBTSHRHTT | |
| SCHEMBL3239413 | 0.67 | TSHR (0.58) | ALDH1A1GAAPKMPOLBTSHR | |
| SCHEMBL756264 | 0.66 | ALDH1A1 (0.54) | ALDH1A1GAAPKMTSHRGLO1 | |
| Potassium SCHEMBL9046394 | 0.65 | ALDH1A1 (0.53) | ALDH1A1GAAPKMTSHRGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877022-B1 | Sulfonylpyrimidine derivatives with anticancer activity | RUDJER BOSKOVIC INST (HR) | 2003-04-16 | — | — | EP | claimed |