Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | PSD | A5PKW4 | 9/20 | 0.51 |
| ▸ | ARF6 | P62330 | 6/20 | 0.48 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31560163 | 0.86 | CRHR1 (0.50) | TP53ARF6MAPT | |
| SCHEMBL23521093 | 0.69 | TP53 (0.58) | TP53MAPT | |
| SCHEMBL13516748 | 0.67 | ARF6 (0.60) | PSDARF6 | |
| SCHEMBL2457427 | 0.67 | HPGD (0.58) | TP53MAPT | |
| SCHEMBL9704830 | 0.66 | CTRC (0.66) | TP53MAPTCTRC | |
| SCHEMBL25362655 | 0.66 | CNR1 (0.38) | TP53ARF6MAPT | |
| SCHEMBL19084551 | 0.66 | ARF6 (0.61) | PSDARF6 | |
| SCHEMBL12439596 | 0.66 | KDM4E (0.48) | — | |
| SCHEMBL19084541 | 0.65 | ARF6 (0.57) | PSDARF6 | |
| SCHEMBL9705291 | 0.65 | CTRC (0.65) | TP53MAPTCTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11413278-B2 | Compounds and methods for promoting stress resistance | HSPA9, ATF4, GPX4 | TP53 2033/4885PSD 962/4885ARF6 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.