Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 11/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | RRM1 | P23921 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248429 | 1.00 | EPHX1 (0.44) | EPHX1NOD1NAAAKDM4EALDH1A1 | |
| SCHEMBL8055730 | 0.98 | EPHX1 (0.41) | EPHX1NOD1NAAAKDM4EALDH1A1 | |
| SCHEMBL9802585 | 0.98 | EPHX1 (0.41) | EPHX1NOD1NAAAKDM4EALDH1A1 | |
| Phosphoric Acid SCHEMBL8213494 | 0.93 | ANPEP (0.44) | EPHX1NOD1NAAAKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9307684 | 0.93 | ALOX15 (0.44) | EPHX1NOD1NAAAKDM4EALDH1A1 | |
| SCHEMBL26225624 | 0.85 | NOD1 (0.46) | EPHX1NOD1CASP2RRM1DPP7 | |
| SCHEMBL7342396 | 0.85 | CA1 (0.44) | EPHX1NOD1CASP2RRM1DPP7 | |
| SCHEMBL14367745 | 0.85 | CA1 (0.44) | EPHX1NOD1CASP2RRM1DPP7 | |
| SCHEMBL21206958 | 0.84 | TGFBR1 (0.36) | KDM4ETLR2 | |
| SCHEMBL23831532 | 0.84 | EPHX1 (0.42) | EPHX1NOD1CASP2RRM1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588196-B1 | INHIBITION OF INFLAMMATION BYSIMULTANEOUS BLOCKADE OF MULTIPLE PROSTANOID RECEPTORS | ALLERGAN INC (US) | 2018-01-24 | — | — | EP | disclosed |
| US-8901159-B2 | Inhibition of inflammation by simultaneous blockade of multiple prostanoid receptors | ALLERGAN, INC. (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140187596-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ALLERGAN, INC. (US) | 2014-07-03 | — | — | US | disclosed |
| EP-2588196-A2 | INHIBITION OF INFLAMMATION BYSIMULTANEOUS BLOCKADE OF MULTIPLE PROSTANOID RECEPTORS | Allergan, Inc. (US) | 2013-05-08 | — | — | EP | disclosed |
| US-20120329843-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | ALLERGAN, INC. | 2012-12-27 | — | — | US | disclosed |
| WO-2012162416-A1 | FATTY ACID AMIDE HYDROLASE INHIBITORS FOR TREATING PAIN | ALLERGAN, INC. (US) | 2012-11-29 | — | — | WO | disclosed |
| US-20120077857-A1 | INHIBITION OF INFLAMMATION BYSIMULTANEOUS BLOCKADE OF MULTIPLE PROSTANOID RECEPTORS | ALLERGAN, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| WO-2012003477-A2 | INHIBITION OF INFLAMMATION BYSIMULTANEOUS BLOCKADE OF MULTIPLE PROSTANOID RECEPTORS | ALLERGAN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120329843-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | FAAH, FAAH2, HRH2 | EPHX1 46/4885NOD1 1780/4885NAAA 63/4885 |
| US-20140187596-A1 | FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN | FAAH, FAAH2, HRH2 | EPHX1 46/4885NOD1 1780/4885NAAA 63/4885 |
| US-20120077857-A1 | INHIBITION OF INFLAMMATION BYSIMULTANEOUS BLOCKADE OF MULTIPLE PROSTANOID RECEPTORS | LTB4R2, LTB4R, PTGIR | EPHX1 298/4885NOD1 728/4885NAAA 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.