Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24893409 | 0.89 | ACACB (0.50) | SHMT2L3MBTL1FASN | |
| SCHEMBL24901393 | 0.87 | ADK (0.50) | ADKPPARGPIK3CACYP1A2DGAT1 | |
| SCHEMBL24893418 | 0.86 | RAB9A (0.47) | MAPT | |
| SCHEMBL24893400 | 0.80 | SHMT2 (0.39) | SHMT2L3MBTL1 | |
| SCHEMBL24893407 | 0.79 | MMP13 (0.46) | — | |
| SCHEMBL24893374 | 0.79 | MEN1 (0.43) | SHMT2 | |
| SCHEMBL24893398 | 0.79 | TERT (0.46) | MAPT | |
| SCHEMBL24893376 | 0.77 | HTT (0.55) | CYP1A2MAPTCYP2C19 | |
| SCHEMBL6818554 | 0.76 | ALB (0.63) | PPARGCYP1A2MAPTCYP2C19FASN | |
| SCHEMBL24893399 | 0.76 | NPC1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023285371-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | UNIVERSITÄT HAMBURG (DE) | 2023-01-19 | — | — | WO | disclosed |
| EP-4119138-A1 | DHODH INHIBITORS AND THEIR USE AS ANTIVIRAL AGENTS | Universität Hamburg (DE) | 2023-01-18 | — | — | EP | disclosed |