SCHEMBL2490975

SCHEMBL2490975

CCC(C)[Si](C)(C)O[Si](C)(C)C(C)CC

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9978573 0.88
SCHEMBL107700 0.88
SCHEMBL9908987 0.84 TSHR (0.30) TSHR
SCHEMBL14338113 0.82
SCHEMBL1315484 0.79
SCHEMBL1313966 0.77 LMNA (0.30)
SCHEMBL1317123 0.77
SCHEMBL15915745 0.75 TSHR (0.30) TSHR
SCHEMBL17865425 0.75
SCHEMBL18456429 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140219903-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2014-08-07 US claimed
CN-103781937-A Film-forming material, sealing film using same, and use of sealing film TOSOH CORP 2014-05-07 CN claimed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US claimed
EP-3558222-B1 WATER-IN-OIL EMULSION COMPRISING A PARTICULAR EMULSIFYING SYSTEM, A LIPOPHILIC CLAY, AND AN ORGANOPOLYSILOXANE ELASTOMER POWDER COATED WITH A SILICONE RESIN OREAL (FR) 2024-04-03 EP disclosed
EP-3558238-B1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL OREAL (FR) 2023-08-23 EP disclosed
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt L'OREAL (FR) 2022-07-05 US disclosed
CN-110099662-B Water-in-oil emulsion comprising a specific emulsifying system, a lipophilic clay and a silicone resin-coated organopolysiloxane elastomer powder 莱雅公司 2022-04-26 CN disclosed
EP-3558216-B1 WATER-IN-OIL EMULSION CONTAINING BAICALIN, A XANTHINE BASE, A VITAMIN B3, AND A POLYVALENT METAL CATION SALT L'ORÉAL (FR) 2020-09-16 EP disclosed
US-10653600-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and two particular distinct silicone oils L'OREAL (FR) 2020-05-19 US disclosed
US-20200085723-A1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID beta,beta-DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL L'OREAL (FR) 2020-03-19 US disclosed
US-20190290570-A1 COMPOSITIONS FOR REMOVING COSMETIC FILMS L'OREAL (FR) 2019-09-26 US disclosed
US-20130142743-A1 COSMETIC PROCESS FOR MAKING-UP AND/OR CARING FOR THE SKIN AND/OR THE LIPS L'OREAL (FR) 2013-06-06 US disclosed
US-20130136705-A1 COSMETIC COMPOSITION COMPRISING AN OIL AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2013-05-30 US disclosed
US-8440211-B2 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2013-05-14 US disclosed
EP-1620068-B1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE OREAL (FR) 2012-05-09 EP disclosed
WO-2011148325-A1 COSMETIC COMPOSITION BASED ON A SUPRAMOLECULAR POLYMER AND A SILICONE FILLER L'OREAL (FR) 2011-12-01 WO disclosed
EP-2380556-A1 Cosmetic composition comprising a volatile fatty phase L'Oréal (FR) 2011-10-26 EP disclosed
US-20090074689-A1 COSMETIC COMPOSITION COMPRISING A VOLATILE FATTY PHASE L'OREAL S.A. 2009-03-19 US disclosed
US-20040197284-A1 Cosmetic composition comprising a volatile fatty phase L'OREAL S.A. (FR) 2004-10-07 US disclosed
US-4902684-A Benzazepine and benzothiazepine derivatives E. R. SQUIBB & SONS, INC. (US) 1990-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10653600-B2 Cosmetic composition comprising a supramolecular compound capable of establishing hydrogen bonds, and two particular distinct silicone oils CHEK1, STIM1, FASN TSHR 4034/4885
US-20130136705-A1 COSMETIC COMPOSITION COMPRISING AN OIL AND A POLYMER BOTH BEARING A HYDROGEN-BOND-GENERATING JOINING GROUP, AND COSMETIC TREATMENT PROCESS SQLE, MMS19, FDFT1 TSHR 3863/4885
US-20190290570-A1 COMPOSITIONS FOR REMOVING COSMETIC FILMS KRT18, CUTA, DSG1 TSHR 4571/4885
US-11376205-B2 Water-in-oil emulsion containing baicalin, a xanthine base, a vitamin B3, and a polyvalent metal cation salt KRT18, BROX, S100B TSHR 4866/4885
US-20200085723-A1 COMPOSITION CONTAINING AN OILY CONTINUOUS PHASE, A LIQUID beta,beta-DIPHENYLACRYLATE UV-SCREENING AGENT, A LIQUID SALICYLATE UV-SCREENING AGENT AND A NON-CYCLIC VOLATILE SILICONE OIL KRT18, CUTA, SKP1 TSHR 4733/4885
US-20130142743-A1 COSMETIC PROCESS FOR MAKING-UP AND/OR CARING FOR THE SKIN AND/OR THE LIPS CUTA, DSG1, LPO TSHR 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.