Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22916030 | 0.95 | OPRM1 (0.41) | OPRM1OPRD1OPRK1MLNRCTSD | |
| SCHEMBL20283586 | 0.93 | GHSR (0.38) | OPRM1OPRD1OPRK1PSMB5MLNR | |
| SCHEMBL22916085 | 0.90 | OPRM1 (0.42) | OPRM1OPRD1OPRK1CTSD | |
| SCHEMBL22916031 | 0.89 | CTSS (0.38) | OPRM1OPRD1OPRK1PSMB5 | |
| SCHEMBL22916029 | 0.88 | GHSR (0.41) | OPRM1OPRD1OPRK1MLNR | |
| SCHEMBL22916013 | 0.86 | MMP1 (0.36) | OPRM1OPRD1OPRK1MMP1MMP2 | |
| SCHEMBL20283587 | 0.85 | CTSD (0.41) | OPRM1OPRD1OPRK1MLNRCTSD | |
| SCHEMBL24917258 | 0.84 | CTSS (0.39) | OPRM1OPRD1OPRK1MLNRCTSD | |
| SCHEMBL20283427 | 0.84 | IDE (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20283589 | 0.83 | IDE (0.41) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560361-B2 | Simplified structural mimetics of AIPS as quorum sensing inhibitors | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560361-B2 | Simplified structural mimetics of AIPS as quorum sensing inhibitors | AIPL1, AIP, PYM1 | OPRM1 1628/4885OPRD1 2470/4885OPRK1 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.