SCHEMBL2492439

SCHEMBL2492439

CCCCCCCC/C=C\CCCCCCCCC1=NCCO1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.42
FAAH O00519 2/20 0.39
TRPV1 Q8NER1 1/20 0.39
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
CDC25C P30307 1/20 0.38
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
GMNN O75496 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
ALOX15 P16050 1/20 0.35
APEX1 P27695 1/20 0.35
CYP2C19 P33261 1/20 0.35
RECQL P46063 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9161754 1.00 EPHX2 (0.42) EPHX2FAAHTRPV1CDC25ACDC25B
SCHEMBL9160070 1.00 EPHX2 (0.42) EPHX2FAAHTRPV1CDC25ACDC25B
SCHEMBL9160076 1.00 EPHX2 (0.42) EPHX2FAAHTRPV1CDC25ACDC25B
SCHEMBL9161764 1.00 EPHX2 (0.42) EPHX2FAAHTRPV1CDC25ACDC25B
SCHEMBL2492444 1.00 EPHX2 (0.42) EPHX2FAAHTRPV1CDC25ACDC25B
SCHEMBL9164484 0.95 TRPV1 (0.40) EPHX2TRPV1ALDH1A1TSHRLMNA
SCHEMBL20750916 0.95 TRPV1 (0.40) EPHX2TRPV1ALDH1A1TSHRLMNA
SCHEMBL9164478 0.95 TRPV1 (0.40) EPHX2TRPV1ALDH1A1TSHRLMNA
SCHEMBL9741629 0.94 ALDH1A1 (0.39) EPHX2FAAHTRPV1CDC25ACDC25B
SCHEMBL10380755 0.91 EPHX2 (0.40) EPHX2FAAHTRPV1CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12508218-B2 Coating compositions COTY INC. (US) 2025-12-30 US disclosed
US-20250152487-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF COTY INC. 2025-05-15 US disclosed
US-20250127694-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF COTY INC. 2025-04-24 US disclosed
US-20250127707-A1 FRAGRANCE FORMULATION COTY INC. 2025-04-24 US disclosed
US-20250032371-A1 ETHANOL-FREE FRAGRANCE CHASSIS COTY INC. 2025-01-30 US disclosed
US-12178896-B2 Fragrance compositions and uses thereof COTY INC. (US) 2024-12-31 US disclosed
US-20230285261-A1 FRAGRANCE COMPOSITION COMPRISING A FRAGRANCE COMPONET AND A NON-ODOROUS FRAGRANCE MODULATOR JPMORGAN CHASE BANK, N.A. 2023-09-14 US disclosed
US-11639406-B2 Acrylic resin with internal plasticizer COLUMBIA INSURANCE COMPANY (US) 2023-05-02 US disclosed
US-20220304914-A1 COATING COMPOSITIONS JPMORGAN CHASE BANK, N.A. 2022-09-29 US disclosed
US-20210361547-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF JPMORGAN CHASE BANK, N.A. 2021-11-25 US disclosed
US-20100093888-A1 POLYLACTIC ACID COMPOSITION TEIJIN LIMITED (JP) 2010-04-15 US disclosed
CN-101622310-A Polylactic acid composition TEIJIN LTD 2010-01-06 CN disclosed
EP-2116576-A1 POLYLACTIC ACID COMPOSITION Teijin Limited (JP) 2009-11-11 EP disclosed
US-7514507-B2 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2009-04-07 US disclosed
US-20070142611-A1 Comb-shaped epoxy resin and method for preparing comb-shaped epoxy resin DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-06-21 US disclosed
EP-0937695-A1 Thickened emulsion compositions for use as propellants and explosives The Lubrizol Corporation (US) 1999-08-25 EP disclosed
US-5936194-A OXIDIZER, OIL FUEL, EMULSIFIER, CARBOXY CONTAINING POLYMER THICKENER, SODIUM THIOCYANATE OR THIOUREA PROMOTER THE LUBRIZOL CORPORATION (US) 1999-08-10 US disclosed
US-5091100-A Fatty triglyceride-in-water solid film high temperature prelube emulsion for hot rolled steel NALCO CHEMICAL COMPANY (US) 1992-02-25 US disclosed
EP-0217194-A1 Microcellular composite energetic materials and method for making same Megabar Corporation (US) 1987-04-08 EP disclosed
US-4632714-A STORAGE STABILITY; WATER PROOFING; MAINTAINING CONTINUOUS PHASE UPON SOLIDIFICATION OF CASTABLE ANHYDROUS EMULSION MEGABAR CORPORATION (US) 1986-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220304914-A1 COATING COMPOSITIONS OR10J3, OR51E2, TAS2R20 EPHX2 1555/4885FAAH 427/4885TRPV1 55/4885
US-12178896-B2 Fragrance compositions and uses thereof FHIT, ALG3, FEM1B EPHX2 377/4885FAAH 4/4885TRPV1 39/4885
US-20250032371-A1 ETHANOL-FREE FRAGRANCE CHASSIS OR51E2, FDFT1, ELANE EPHX2 1260/4885FAAH 27/4885TRPV1 523/4885
US-20250127694-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF TRPA1, TRPV1, NAA40 EPHX2 1291/4885FAAH 20/4885TRPV1 2/4885
US-20250127707-A1 FRAGRANCE FORMULATION PUF60, POLM, ADH5 EPHX2 850/4885FAAH 20/4885TRPV1 34/4885
US-20230285261-A1 FRAGRANCE COMPOSITION COMPRISING A FRAGRANCE COMPONET AND A NON-ODOROUS FRAGRANCE MODULATOR OR51E2, TRPA1, FAM120A EPHX2 1244/4885FAAH 27/4885TRPV1 6/4885
US-20210361547-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF FHIT, ALG3, FEM1B EPHX2 377/4885FAAH 4/4885TRPV1 39/4885
US-12508218-B2 Coating compositions TAS2R40, TAS2R20, TAS2R10 EPHX2 2935/4885FAAH 2953/4885TRPV1 106/4885
US-20250152487-A1 FRAGRANCE COMPOSITIONS AND USES THEREOF FHIT, ALG3, FEM1B EPHX2 377/4885FAAH 4/4885TRPV1 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.