Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.37 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30729456 | 1.00 | ALDH1A1 (0.37) | ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL26021960 | 0.82 | CYP11B2 (0.34) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22393902 | 0.81 | PIK3CD (0.40) | ALDH1A1ALOX15MAPTCYP1A2KDM4E | |
| SCHEMBL22313716 | 0.78 | APP (0.35) | ALDH1A1ALOX15SMN1; SMN2MAPTKDM4E | |
| SCHEMBL22214063 | 0.76 | LMNA (0.46) | ALDH1A1ALOX15CA2MEN1RAB9A | |
| SCHEMBL21035191 | 0.74 | ALDH1A1 (0.59) | ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL24962104 | 0.74 | TRPA1 (0.33) | LMNATRPA1 | |
| SCHEMBL16261248 | 0.73 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2TYRCA2POLB | |
| SCHEMBL15889361 | 0.73 | PIM1 (0.44) | ALDH1A1ALOX15SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL2419516 | 0.73 | MEN1 (0.40) | SMN1; SMN2TDP1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230054781-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | RBM17, SF3B1, SF3B5 | ALDH1A1 3964/4885ALOX15 677/4885SMN1; SMN2 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.