Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30257342 | 0.76 | ADORA1 (0.56) | ADORA3ADORA1ADORA2AHTR3ALTA4H | |
| SCHEMBL25079149 | 0.73 | HTR3A (0.48) | ADORA3ADORA1ADORA2AHTR3AMAOB | |
| SCHEMBL7354904 | 0.70 | HTR3A (0.61) | ADORA3ADORA1ADORA2AHTR3AMAPT | |
| SCHEMBL7356830 | 0.68 | HTR3A (0.58) | ADORA3ADORA1ADORA2AHTR3AMAOB | |
| SCHEMBL31444008 | 0.68 | PKM (0.43) | ADORA3MAOBMAPTTDP1L3MBTL1 | |
| SCHEMBL20389071 | 0.67 | ALKBH5 (0.43) | MAPTNPC1RAB9A | |
| SCHEMBL30706223 | 0.66 | LMNA (0.37) | MAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL25079216 | 0.66 | MAPT (0.41) | HTR3AAPPMAPTTDP1 | |
| SCHEMBL15264273 | 0.66 | APP (0.69) | APPMAOBMAPTMAPK1TDP1 | |
| SCHEMBL25079151 | 0.65 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AHTR3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023531-A1 | ESTROGEN RECEPTOR DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2023-02-23 | — | — | WO | disclosed |