SCHEMBL250888

SCHEMBL250888

CCCCCOC[C@@H](O)COP(=O)(O)O

nearest known ligand 0.97

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 6/20 0.97
LPAR1 Q92633 13/20 0.67
LPAR3 Q9UBY5 10/20 0.67
LPAR2 Q9HBW0 7/20 0.59
LPAR4 Q99677 5/20 0.59
LPAR6 P43657 4/20 0.59
ENPP2 Q13822 3/20 0.59
USP2 O75604 1/20 0.56
HTT P42858 1/20 0.54
P2RY10 O00398 1/20 0.54
CES2 O00748 1/20 0.51
TRPV1 Q8NER1 1/20 0.51
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45056 1.00 LPAR5 (0.97) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258161 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL7820593 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258032 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258118 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL7829804 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL12621099 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL258094 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL28064781 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4
SCHEMBL26603866 0.98 LPAR5 (1.00) LPAR5LPAR1LPAR3LPAR2LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4031685-B1 IN VITRO FERTILISATION (IVF) EMBRYO VIABILILITY AND QUALITY ASSAY UNIV TARTU (EE) 2024-07-10 EP claimed
WO-2019182440-A1 METHOD FOR PRODUCING CELL WALL-TARGETING ANTIBIOTICS IN SUSCEPTIBLE BACTERIA TECHNISCHE UNIVERSTITEIT DELFT (NL) 2019-09-26 WO claimed
WO-2011034263-A1 METHOD FOR PREDICTING A DRUG TARGET IN PATHOGENIC MICROORGANISMS USING AN ESSENTIAL METABOLITE 한국과학기술원 (KR) 2011-03-24 WO claimed
WO-2011034397-A2 METHOD FOR PREDICTING DRUG TARGETS AND SCREENING FOR DRUGS FOR PATHOGENIC MICROORGANISMS USING ESSENTIAL METABOLITES 한국과학기술원 (KR) 2011-03-24 WO claimed
JP-4301571-B2 2009-07-22 JP claimed
US-20070123492-A1 Analogs of lysophosphatidic acid and methods of making and using thereof NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-05-31 US claimed
EP-1615937-A2 ANALOGS OF LYSOPHOSPHATIDIC ACID AND METHODS OF MAKING AND USING THEREOF University of Utah Research Foundation (US) 2006-01-18 EP claimed
WO-2004092188-A2 ANALOGS OF LYSOPHOSPHATIDIC ACID AND METHODS OF MAKING AND USING THEREOF UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2004-10-28 WO claimed
EP-0917580-A1 DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS MONSANTO COMPANY (US) 1999-05-26 EP claimed
EP-0837630-A4 PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY UNIV CALIFORNIA (US) 1998-11-25 EP claimed
EP-0837630-A1 PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-04-29 EP claimed
WO-1998003664-A1 DEFORMYLATION OF f-MET PEPTIDES IN BACTERIAL EXPRESSION SYSTEMS MONSANTO COMPANY (US) 1998-01-29 WO claimed
WO-1996039831-A1 PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-19 WO claimed
US-5411947-A converting drugs having suitable functional groups to 1-O-alkyl-, 1-O-acyl-, 1-S-acyl, and 1-S-alkyl-sn-glycero-3-phosphate derivatives; drugs such as AZT, cladribine, AICA-Riboside VESTAR, INC. (US) 1995-05-02 US claimed
US-12631643-B2 Tissue-derived extracellular vesicles and their use as diagnostics EXOCURE SWEDEN AB (SE) 2026-05-19 US disclosed
US-12600978-B2 Process for producing lipids Nuseed Global Innovation Ltd. (GB) 2026-04-14 US disclosed
US-12516083-B2 Nucleophilic catalysts for oxime linkage TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2026-01-06 US disclosed
EP-0673424-A1 DNA ENCODING 2-ACYLTRANSFERASES NICKERSON BIOCEM LIMITED (GB) 1995-09-27 EP disclosed
US-5411947-A converting drugs having suitable functional groups to 1-O-alkyl-, 1-O-acyl-, 1-S-acyl, and 1-S-alkyl-sn-glycero-3-phosphate derivatives; drugs such as AZT, cladribine, AICA-Riboside VESTAR, INC. (US) 1995-05-02 US disclosed
WO-1994013814-A1 DNA ENCODING 2-ACYLTRANSFERASES NICKERSON BIOCEM LIMITED (GB) 1994-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600978-B2 Process for producing lipids DGAT1, DGAT2, SOAT2 LPAR5 203/4885LPAR1 110/4885LPAR3 171/4885
US-20070123492-A1 Analogs of lysophosphatidic acid and methods of making and using thereof LPAR4, LPAR2, LPAR5 LPAR5 3/4885LPAR1 6/4885LPAR3 7/4885
US-12631643-B2 Tissue-derived extracellular vesicles and their use as diagnostics DNASE1, RNASE1, DNASE1L3 LPAR5 2096/4885LPAR1 2493/4885LPAR3 2476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.