Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340887 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL4482770 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL30377710 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL2599260 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTCASP3CA12 | |
| SCHEMBL3389540 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTCASP3CA12 | |
| SCHEMBL4309242 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTCASP3GLSMAOB | |
| SCHEMBL14318320 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTCASP3CA12 | |
| SCHEMBL2599263 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTCASP3CA12 | |
| SCHEMBL3379010 | 0.80 | ELANE (0.51) | ALDH1A1KMT2ACASP3CA12CA9 | |
| SCHEMBL17280822 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KMT2AMAPTCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462652-B | Alpha-mangostin derivative and preparation method and application thereof | 中国农业大学 | 2025-05-06 | — | — | CN | disclosed |
| CN-116462652-A | Alpha-mangostin derivative and preparation method and application thereof | 中国农业大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-107540647-B | -amino alkyl furan phenol ether and preparation method and application thereof | 湖南大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-107540647-A | δ aminoalkyl furans phenolic ethers and preparation method and application | 湖南大学 | 2018-01-05 | — | — | CN | disclosed |
| US-20130217672-A1 | (+)-3-HYDROXYMORPHINAN-BASED POLYCYCLE DERIVATIVES | GREEN CROSS CORPORATION (KR) | 2013-08-22 | — | — | US | disclosed |
| EP-2074083-B1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-06-19 | — | — | EP | disclosed |
| EP-2569320-A2 | (+)-3-HYDROXYMORPHINAN-BASED POLYCYCLE DERIVATIVES AS NEUROPROTECTANTS | Green Cross Corporation (KR) | 2013-03-20 | — | — | EP | disclosed |
| EP-2057116-B1 | NEW PHENYLSULFAMOYL BENZAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT (HU) | 2013-02-13 | — | — | EP | disclosed |
| US-20130029991-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BEKE GYULA (HU) | 2013-01-31 | — | — | US | disclosed |
| US-20120295910-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BEKE GYULA (HU) | 2012-11-22 | — | — | US | disclosed |
| EP-1966142-A2 | NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007072092-A2 | NEW PHENANTHRIDINE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2007-06-28 | — | — | WO | disclosed |
| US-20070049604-A1 | Piperazinylalkylpyrazole derivatives useful as selective T-type calcium channel blockers and preparation method thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2007-03-01 | — | — | US | disclosed |
| EP-1757590-A1 | Piperazinylalkylpyrazole derivatives useful as selective T-type calcium channel blockers and preparation method thereof | Korea Institute of Science and Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| US-20020068827-A1 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 ( NK-3 ) - and neurokinin 2 ( NK-3 ) receptor antagonists | SMITHKLINE BEECHAM S.P.A. | 2002-06-06 | — | — | US | disclosed |
| EP-1019377-A1 | QUINOLINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS NEUROKININ 3 (NK-3)- AND NEUROKININ 2 (NK-2) RECEPTOR ANTAGONISTS. | Smithkline Beecham S.p.A. (IT) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997019926-A1 | QUINOLINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS NEUROKININ 3 (NK-3)- AND NEUROKININ 2 (NK-2) RECEPTOR ANTAGONISTS. | SMITHKLINE BEECHAM S.P.A. (IT) | 1997-06-05 | — | — | WO | disclosed |
| EP-0111281-B1 | NEW CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-06-06 | — | — | EP | disclosed |
| US-4719206-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-01-12 | — | — | US | disclosed |
| US-4584290-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295910-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BDKRB1, BDKRB2, HRH4 | ALDH1A1 3460/4885KMT2A 2478/4885MAPT 3406/4885 |
| US-20130029991-A1 | New Phenylsulfamoyl Benzamide Derivatives as Bradykinin Antagonists | BDKRB1, BDKRB2, HRH4 | ALDH1A1 3348/4885KMT2A 2406/4885MAPT 3401/4885 |
| US-20070049604-A1 | Piperazinylalkylpyrazole derivatives useful as selective T-type calcium channel blockers and preparation method thereof | CACNA1I, CACNA1G, CACNA1H | ALDH1A1 2701/4885KMT2A 4312/4885MAPT 2721/4885 |
| US-20130217672-A1 | (+)-3-HYDROXYMORPHINAN-BASED POLYCYCLE DERIVATIVES | HTT, PARK7, HTR3A | ALDH1A1 2197/4885KMT2A 4458/4885MAPT 77/4885 |
| US-20020068827-A1 | Quinoline-4-carboxamide derivatives, their preparation and their use as neurokinin 3 ( NK-3 ) - and neurokinin 2 ( NK-3 ) receptor antagonists | TAC3, TACR2, TACR1 | ALDH1A1 2059/4885KMT2A 733/4885MAPT 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.