Sugi Predict

Sugi Predict / Compounds / SCHEMBL2518889

SCHEMBL2518889

SCHEMBL2518889

CC1C=CN(c2ccccc2)C(=O)N1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.36
▸ MAPK1 P28482 2/20 0.36
▸ GAA P10253 2/20 0.35
▸ MAOA P21397 1/20 0.35
▸ G6PD P11413 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ MEN1 O00255 3/20 0.34
▸ RAB9A P51151 2/20 0.34
▸ NPC1 O15118 1/20 0.34
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ LOX P28300 1/20 0.34
▸ LOXL3 P58215 1/20 0.34
▸ LOXL4 Q96JB6 1/20 0.34
▸ LOXL2 Q9Y4K0 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ GSK3A P49840 1/20 0.33
▸ GSK3B P49841 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5711521 0.98 KMT2A (0.35) KMT2AMAPK1GAAMAOAG6PD
Sulfuric Acid SCHEMBL6011119 0.92 KDM4E (0.35) KMT2AMAPK1GAAMAOAG6PD
Sulfuric Acid SCHEMBL6011118 0.89 PTGS1 (0.36) KMT2AMAPK1L3MBTL1PTGS1PTGS2
SCHEMBL2517230 0.79 ALDH1A1 (0.37) KMT2AGAAMEN1SMN1; SMN2CYP1A2
Hydrochloric Acid SCHEMBL5711553 0.77 ALDH1A1 (0.36) GAASMN1; SMN2CYP1A2CYP2C9CYP2C19
Sulfuric Acid SCHEMBL6011203 0.74 ALDH1A1 (0.33) KMT2AGAAL3MBTL1MEN1SMN1; SMN2
Sulfuric Acid SCHEMBL6011200 0.72 ALDH1A1 (0.32) KMT2AGAAMEN1SMN1; SMN2PTGS1
SCHEMBL6713101 0.68 MAOA (0.48) KMT2AGAAMAOAG6PDL3MBTL1
SCHEMBL2517218 0.67 MAOA (0.41) KMT2AMAPK1GAAMAOAMEN1
SCHEMBL9835334 0.66 MAOA (0.47) KMT2AGAAMAOAG6PDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2358343-B1 METHOD FOR DECOLOURING KERATINOUS FIBRES HENKEL AG & CO KGAA (DE) 2016-10-19 — — EP claimed
EP-1965753-B1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO KGAA (DE) 2013-09-04 — — EP claimed
US-8268015-B2 Method for decolorizing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2012-09-18 — — US claimed
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers HENKEL AG & CO. KGAA (DE) 2011-10-13 — — US claimed
US-7799096-B2 Agent for dyeing keratin-containing fibers HENKEL AG & CO. KGAA (DE) 2010-09-21 — — US claimed
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS HENKEL AG & CO. KGAA (DE) 2010-03-18 — — US claimed
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS HENKEL AG & CO. KGAA (DE) 2010-02-18 — — US claimed
EP-2014275-A2 Kit for preparing storage-stable formulations Henkel AG & Co. KGaA (DE) 2009-01-14 — — EP claimed
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR HENKEL AG & CO. KGAA (DE) 2008-12-11 — — US claimed
US-7393367-B2 Agent for dyeing keratin-based fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-07-01 — — US claimed
US-20080104772-A1 AGENT FOR DYEING KERATIN-BASED FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-08 — — US claimed
EP-1534227-B1 AGENTS USED FOR DYEING KERATINOUS FIBERS HENKEL KGAA (DE) 2006-12-27 — — EP claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 — — US disclosed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 — — US disclosed
CN-114746069-A Three-step multi-tone hair dyeing method 汉高股份有限及两合公司 2022-07-12 — — CN disclosed
WO-2021110306-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2021-06-10 — — WO disclosed
EP-1813260-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed
EP-1813261-A2 Bleaching method for keratinic fibres Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed
EP-1813259-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed
EP-1813258-A2 Bleaching and/or colouring agent with reduced potential for irritation Henkel Kommanditgesellschaft auf Aktien (DE) 2007-08-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110247644-A1 Method for Decolorizing Keratin-Containing Fibers KRT18, PLOD3, DSG1 KMT2A 228/4885MAPK1 772/4885GAA 3158/4885
US-20080104772-A1 AGENT FOR DYEING KERATIN-BASED FIBERS KRT18, KAT5, H1-5 KMT2A 2567/4885MAPK1 2184/4885GAA 4691/4885
US-20100064450-A1 AGENT FOR DYEING KERATIN-CONTAINING FIBERS KRT18, CRYAA, CKAP4 KMT2A 1270/4885MAPK1 919/4885GAA 3583/4885
US-20100037909-A1 SUBSTANCES FOR DYEING KERATINOUS FIBERS KRT18, H1-10, COL1A1 KMT2A 1767/4885MAPK1 1292/4885GAA 3140/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO KMT2A 631/4885MAPK1 567/4885GAA 2405/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO KMT2A 631/4885MAPK1 567/4885GAA 2405/4885
US-20080301885-A1 REVERSIBLY CHANGEABLE HAIR COLOR TYR, CBR3, COXFA4L2 KMT2A 632/4885MAPK1 1559/4885GAA 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.