SCHEMBL252333

SCHEMBL252333

c1cnc(-c2cccc(-c3cnc(-c4cccnc4)s3)n2)nc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 2/20 0.57
CYP19A1 P11511 3/20 0.49
CYP2A6 P11509 4/20 0.47
RAB9A P51151 3/20 0.44
KDM4E B2RXH2 3/20 0.44
NPC1 O15118 2/20 0.44
ALDH1A1 P00352 1/20 0.44
AXL P30530 1/20 0.43
PBRM1 Q86U86 1/20 0.43
MKNK1 Q9BUB5 1/20 0.43
MKNK2 Q9HBH9 1/20 0.43
TP53 P04637 1/20 0.41
PKM P14618 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
DCTPP1 Q9H773 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29360785 1.00 HPGDS (0.57) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL2732549 0.90 HPGDS (0.55) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL12278751 0.89 HPGDS (0.51) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL18173959 0.88 HPGDS (0.59) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL12279056 0.87 HPGDS (0.58) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL678011 0.87 HPGDS (0.42) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL9973683 0.86 HPGDS (0.52) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL12279597 0.85 HPGDS (0.50) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL12279387 0.85 HPGDS (0.50) HPGDSCYP19A1CYP2A6RAB9AKDM4E
SCHEMBL12278878 0.84 HPGDS (0.55) HPGDSCYP19A1CYP2A6RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1030 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2025-11-06 US claimed
EP-4640052-A1 MIXTURES OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS WITH AT LEAST ONE FURTHER PESTICIDE I BASF SE (DE) 2025-10-29 EP claimed
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS PI INDUSTRIES LTD. (IN) 2024-07-11 US claimed
WO-2024104813-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
WO-2024104814-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES BASF SE (DE) 2024-05-23 WO claimed
CN-117396074-A Fungicidal compositions containing oxadiazole compounds PI工业有限公司 2024-01-12 CN claimed
US-11839214-B2 Fungicidal mixture comprising substituted pyridines BASF SE (DE) 2023-12-12 US claimed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 CN claimed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 CN claimed
CN-103619173-A Active compound combinations comprising (thio) carboxamide derivatives and insecticidal, acaricidal or nematicidal active compounds BAYER IP GMBH 2014-03-05 CN claimed
EP-2699092-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND Bayer Intellectual Property GmbH (DE) 2014-02-26 EP claimed
US-20140051576-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2014-02-20 US claimed
WO-2013092350-A1 N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYL SULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES BAYER CROPSCIENCE AG (DE) 2013-06-27 WO claimed
EP-2606726-A1 N-Arylamidine-substituted trifluoroethylsulfide derivatives as acaricides and insecticides Bayer CropScience AG (DE) 2013-06-26 EP claimed
WO-2013087709-A1 ACTIVE INGREDIENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-06-20 WO claimed
EP-2604118-A1 Active ingredient combinations having insecticidal and acaricidal properties Bayer CropScience AG (DE) 2013-06-19 EP claimed
CN-103068235-A active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG 2013-04-24 CN claimed
WO-2012143125-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND BAYER CROPSCIENCE AG (DE) 2012-10-26 WO claimed
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties BAYER CROPSCIENCE AG (DE) 2011-12-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11839214-B2 Fungicidal mixture comprising substituted pyridines ME1, DPM1, TH HPGDS 4772/4885CYP19A1 764/4885CYP2A6 261/4885
US-20250338849-A1 FUNGICIDAL MIXTURE COMPRISING SUBSTITUTED PYRIDINES ME1, DPM1, ERG28 HPGDS 4755/4885CYP19A1 956/4885CYP2A6 320/4885
US-20240225002-A1 FUNGICIDAL COMPOSITION CONTAINING OXADIAZOLE COMPOUNDS OXA1L, NOX1, NOX3 HPGDS 4715/4885CYP19A1 175/4885CYP2A6 1539/4885
US-20140051576-A1 ACTIVE COMPOUND COMBINATIONS COMPRISING A (THIO)CARBOXAMIDE DERIVATIVE AND AN INSECTICIDAL OR ACARICIDAL OR NEMATICIDAL ACTIVE COMPOUND AADAC, TUBA3C, ACACA HPGDS 4683/4885CYP19A1 1537/4885CYP2A6 2330/4885
US-20110311503-A1 Active ingredient combinations having insecticidal and acaricidal properties ACHE, ACAT1, ACAT2 HPGDS 3777/4885CYP19A1 242/4885CYP2A6 1310/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.