Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 1/20 | 0.30 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.30 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253115 | 0.79 | TSHR (0.44) | TSHRTDP1CYP3A4NPSR1PKM | |
| SCHEMBL11819243 | 0.79 | — | — | |
| SCHEMBL2526154 | 0.78 | TSHR (0.43) | TSHRTDP1CYP3A4NPSR1PKM | |
| Ammonia Solution, Strong SCHEMBL28125183 | 0.78 | TSHR (0.43) | TSHRTDP1CYP3A4NPSR1PKM | |
| SCHEMBL15912136 | 0.76 | TSHR (0.42) | TSHRTDP1CYP3A4NPSR1PKM | |
| SCHEMBL8919856 | 0.76 | TSHR (0.46) | TSHRTDP1CYP3A4NPSR1PKM | |
| SCHEMBL15912166 | 0.74 | TSHR (0.44) | TSHRTDP1CYP3A4NPSR1PKM | |
| SCHEMBL28716260 | 0.74 | TSHR (0.41) | TSHRTDP1CYP3A4NPSR1PKM | |
| SCHEMBL28541190 | 0.73 | TSHR (0.44) | TSHRTDP1CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL3140306 | 0.73 | TDP1 (0.37) | TSHRTDP1CYP3A4NPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004082655-A1 | MEDICATED SKIN CLEANSING PRODUCTS COMPRISING AN ANTIMYCOTIC AGENT | AGIS INDUSTRIES (1983) LTD. (IL) | 2004-09-30 | — | — | WO | claimed |
| WO-2004024120-A2 | MEDICATED SKIN CLEANSING PRODUCTS COMPRISING AN ANTIMYCOTIC AGENT | BIANCO GIL (IL) | 2004-03-25 | — | — | WO | claimed |
| WO-2024136513-A1 | COMPOSITION FOR PROMOTING HAIR GROWTH, COMPRISING STURGEON MUCUS AS ACTIVE INGREDIENT | 주식회사 에셀바이오팜 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024136261-A1 | ANTI-INFLAMMATORY OR ANTIOXIDANT COMPOSITION COMPRISING BENZYL CAFFEATE AS ACTIVE INGREDIENT | 동아대학교 산학협력단 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024136517-A1 | COMPOSITION CONTAINING STURGEON MUCILAGE AS ACTIVE INGREDIENT FOR WOUND HEALING OR ACNE TREATMENT | 순천향대학교 산학협력단 | 2024-06-27 | — | — | WO | disclosed |
| WO-2024128690-A1 | INNATE IMMUNOMODULATORY EFFECT OF GINSENG BERRY POLYSACCHARIDES IN IMMUNOSUPPRESSED STATE | 강릉원주대학교산학협력단 | 2024-06-20 | — | — | WO | disclosed |
| CN-118161520-A | Lipolytic composition using surface-modified gas-generating nanoparticles | 超新星生物有限公司 | 2024-06-11 | — | — | CN | disclosed |
| WO-2024085695-A1 | NOVEL ALTIRATINIB DERIVATIVE, MANUFACTURING METHOD THEREFOR, AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION, ALLEVIATION, OR TREATMENT OF SKIN PIGMENTATION | 재단법인 아산사회복지재단 | 2024-04-25 | — | — | WO | disclosed |
| US-20240099955-A1 | SKINCARE COMPOSITIONS AND METHODS OF USE THEREOF | HTL BIOTECHNOLOGY INNOVATION INC. | 2024-03-28 | — | — | US | disclosed |
| CN-114828834-B | Lipolytic composition using surface-modified gas-generating nanoparticles | 超新星生物有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-11896706-B2 | Composition for preventing hair loss or promoting hair growth, comprising, as active ingredient, mixed extract of cucumber, eggplant and snail extracts as active ingredient | OGADAL INC. (KR) | 2024-02-13 | — | — | US | disclosed |
| US-4157920-A | Novel precipitated siliceous products and methods for their use and production | J. M. HUBER CORPORATION (US) | 1979-06-12 | — | — | US | disclosed |
| US-4154815-A | Zinc and enzyme toothpowder dentifrice | LEVER BROTHERS COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4152418-A | Zinc and enzyme mouthwash and mouthwash concentrate for reducing dental plaque and calculus formation | LEVER BROTHERS COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4132806-A | VISCOSITY CONTROL AGENTS FOR COSMETICS AND PHARMACEUTICALS | J. M. HUBER CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |
| US-4082841-A | ZINC SALT AND AN ENZYME | LEVER BROTHERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |
| US-4067746-A | Amorphous precipitated silicas and methods for their preparation | J. M. HUBER CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4040858-A | ADDUCT OF ALUMINUM, MAGNESIUM, ZINC OR CALCIUM | J. M. HUBER CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4015996-A | ALUMINUM, MAGNESIUM, CALCIUM OR ZINC CATIONS | J. M. HUBER CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-3988162-A | Amorphous precipitated silica products and method for their production | J. M. HUBER CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |