Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27969788 | 1.00 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Ammonia Solution, Strong SCHEMBL31326000 | 0.96 | MEN1 (0.38) | TSHRMEN1ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL17610865 | 0.96 | MEN1 (0.38) | TSHRMEN1ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL31208483 | 0.96 | MEN1 (0.38) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL2698666 | 0.96 | TSHR (0.43) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Sodium Persulfate SCHEMBL9188 | 0.96 | TSHR (0.43) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Sulfuric Acid SCHEMBL8407341 | 0.92 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Ammonia Solution, Strong SCHEMBL4675691 | 0.92 | MEN1 (0.31) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL31508284 | 0.92 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| SCHEMBL31390311 | 0.92 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704628-A | A kind of method and device preparing retarding water reducer | 天水师范学院 | 2019-05-03 | — | — | CN | claimed |
| CN-102776802-B | Reinforcing agent for papermaking and preparation method thereof | EVER FIRST WISE FUND BEIJING SCIENCE AND TECHNOLOGY INC COMPANY | 2014-08-06 | — | — | CN | claimed |
| CN-103194917-A | Desizing-free polyacrylate emulsion slurry for one-step dyeing and weaving and preparation method thereof | GUANGZHOU WEIJIA ANDA NEW MATERIALS TECHNOLOGY CO LTD | 2013-07-10 | — | — | CN | claimed |
| CN-102776802-A | Reinforcing agent for papermaking and preparation method thereof | EVER FIRST WISE FUND BEIJING SCIENCE AND TECHNOLOGY INC COMPANY | 2012-11-14 | — | — | CN | claimed |
| CN-114085377-B | Preparation of polyaniline/carbon nano tube composite material and application of polyaniline/carbon nano tube composite material in sodium-based double-ion battery | 南开大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-115368653-A | Conveyor belt adhesive containing reclaimed rubber and preparation method thereof | 保定三源橡胶有限公司 | 2022-11-22 | — | — | CN | disclosed |
| EP-2722312-B1 | METHOD OF INHIBITING CORROSION AND DEPOSITION IN DESALINATION SYSTEMS | NALCO CO (US) | 2020-07-08 | — | — | EP | disclosed |
| EP-2125626-B1 | METHOD OF INHIBITING SCALE FORMATION AND DEPOSITION IN DESALINATION SYSTEMS | NALCO CO (US) | 2019-06-26 | — | — | EP | disclosed |
| CN-109704628-A | A kind of method and device preparing retarding water reducer | 天水师范学院 | 2019-05-03 | — | — | CN | disclosed |
| CN-106279520-B | A kind of drilling fluid amide polymer shale control agent and preparation method thereof | 成都西油华巍科技有限公司 | 2018-10-12 | — | — | CN | disclosed |
| US-9133046-B2 | Method of inhibiting scale formation and deposition in desalination systems | NALCO COMPANY (US) | 2015-09-15 | — | — | US | disclosed |
| CN-103194917-B | Desizing-free polyacrylate emulsion slurry for one-step dyeing and weaving and preparation method thereof | GUANGZHOU WEIJIA ANDA NEW MATERIALS TECHNOLOGY CO., LTD. (CN) | 2014-10-08 | — | — | CN | disclosed |
| WO-1996013509-A1 | FLUOROALKENYL COMPOUNDS AND THEIR USE AS PEST CONTROL AGENTS | MONSANTO COMPANY (US) | 1996-05-09 | — | — | WO | disclosed |
| US-5147964-A | Derivatized tannin grafted with acrylamide or 2-acrylamido-2-methylpropane sulfonic acid | NALCO CHEMICAL COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-5134215-A | Selected from the group of acrylamido-2-methylpropanesulfonic acid and acrylamide; stability | NALCO CHEMICAL COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| WO-1991010498-A1 | STRONGLY ACIDIC MICROPOROUS MEMBRANES FOR CATIONIC EXCHANGE | GELMAN SCIENCES, INC. (US) | 1991-07-25 | — | — | WO | disclosed |
| US-4980433-A | WATER SOLUBLE POLYMER; WATER TREATMENT | BETZ LABORATORIES, INC. (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0402768-A2 | water-based printing compositions | PPG INDUSTRIES, INC. (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4954556-A | QUICK-DRYING | PPG INDUSTRIES, INC. (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0317906-A2 | Water-based ink compositions | PPG INDUSTRIES, INC. (US) | 1989-05-31 | — | — | EP | disclosed |