Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ammonia Solution, Strong. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2532743 | 1.00 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Ammonia Solution, Strong SCHEMBL31326000 | 0.96 | MEN1 (0.38) | TSHRMEN1ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL17610865 | 0.96 | MEN1 (0.38) | TSHRMEN1ALDH1A1KMT2A | |
| Ammonia Solution, Strong SCHEMBL31208483 | 0.96 | MEN1 (0.38) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL2698666 | 0.96 | TSHR (0.43) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Sodium Persulfate SCHEMBL9188 | 0.96 | TSHR (0.43) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Sulfuric Acid SCHEMBL8407341 | 0.92 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| Ammonia Solution, Strong SCHEMBL4675691 | 0.92 | MEN1 (0.31) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL31508284 | 0.92 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL | |
| SCHEMBL31390311 | 0.92 | TSHR (0.40) | TSHRMEN1ALDH1A1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-217613971-U | Ammonia absorption liquid preparation equipment | 亚泰电化有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-108102025-A | A kind of embossing compound special-purpose aqueous glue of PE and preparation method thereof | 广东佰合新材料科技股份有限公司 | 2018-06-01 | — | — | CN | disclosed |
| CN-108003816-A | A kind of compound special-purpose aqueous glue of aluminizer and preparation method thereof | 广东佰合新材料科技股份有限公司 | 2018-05-08 | — | — | CN | disclosed |
| CN-107987758-A | A kind of kraft compounded special-purpose aqueous glue and preparation method thereof | 广东佰合新材料科技股份有限公司 | 2018-05-04 | — | — | CN | disclosed |
| CN-107936880-A | A kind of non-woven fabric compounded special-purpose aqueous glue and preparation method thereof | 广东佰合新材料科技股份有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107936879-A | A kind of compound special-purpose aqueous glue of aluminium foil and preparation method thereof | 广东佰合新材料科技股份有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-103843370-B | The piezoelectric microphones being made on glass | 追踪有限公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-103843370-A | Piezoelectric microphone fabricated on glass | QUALCOMM MEMS TECHNOLOGIES INC | 2014-06-04 | — | — | CN | disclosed |
| CN-103843368-A | Piezoelectric microphone made on glass | QUALCOMM MEMS TECHNOLOGIES INC | 2014-06-04 | — | — | CN | disclosed |