SCHEMBL254145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17836993	0.86	HSD11B1 (0.46)	HPGDALDH1A1MAPTCYP1A1CYP1B1
	SCHEMBL8895421	0.86	WDR5 (0.50)	HPGDKDM4EALDH1A1MEN1KMT2A
	SCHEMBL17841056	0.86	CDC25B (0.49)	HPGDKDM4EALDH1A1MEN1KMT2A
	SCHEMBL20442253	0.83	ALDH1A1 (0.41)	HPGDKDM4EALDH1A1LMNAHTT
	SCHEMBL485270	0.82	CXCR2 (0.46)	HPGDKDM4EALDH1A1MEN1KMT2A
	SCHEMBL2718494	0.80	SLC40A1 (0.47)	KDM4EALDH1A1
	SCHEMBL7513949	0.80	NCEH1 (0.58)	KDM4EMEN1KMT2ANCEH1LMNA
	SCHEMBL18566637	0.80	KDM4E (0.42)	HPGDKDM4EALDH1A1NPSR1MEN1
	SCHEMBL27693456	0.79	LMNA (0.47)	KDM4EALDH1A1KMT2AMAPTLMNA
	SCHEMBL4467822	0.78	PLK1 (0.44)	KDM4EALDH1A1MEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.