Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.54 |
| ▸ | MASP2 | O00187 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21262437 | 0.83 | NQO2 (0.41) | PLAUPRSS1PRSS3NOS3NOS1 | |
| SCHEMBL24964824 | 0.81 | LMNA (0.54) | PLAUMAPTNPC1RAB9ACYP3A4 | |
| SCHEMBL24514392 | 0.78 | LOXL2 (0.59) | PLAUPRSS1PRSS3NOS3NOS1 | |
| SCHEMBL21285852 | 0.75 | NNMT (0.52) | PLAUMASP2THPONOS3NOS2 | |
| SCHEMBL18480045 | 0.74 | PLAU (0.59) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL22143896 | 0.74 | TSHR (0.55) | CYP19A1ESR1ESR2NOS1MAPK1 | |
| SCHEMBL25659977 | 0.71 | ADRA2A (0.38) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL150756 | 0.71 | PLAU (1.00) | PLAUMASP2THPOF2PRSS1 | |
| Acetic Acid SCHEMBL7398032 | 0.70 | MASP2 (0.74) | PLAUMASP2THPOF2PRSS1 | |
| SCHEMBL22143974 | 0.69 | PLAU (0.35) | PLAUMASP2THPOF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4183783-A1 | IMMUNOMODULATOR | Hitgen Inc. (CN) | 2023-05-24 | — | — | EP | disclosed |